Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for PARP2 (gene)


Gene Symbol:
PARP2 Homo sapiens Homo sapiens
Full name:
poly(ADP-ribose) polymerase 2
Synonyms:
ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2, poly [ADP-ribose] polymerase 2, ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2, ADP-ribosyltransferase diphtheria toxin-like 2, ADPRT-2, NAD(+) ADP-ribosyltransferase 2, hPARP-2, poly (ADP-ribose) polymerase family, member 2, poly (ADP-ribosyl) transferase-like 2, poly[ADP-ribose] synthase 2, poly[ADP-ribose] synthetase 2
Genomic Location:
Chr 14: 19881613-19895903
Description:
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 14
14q11.2





GO Molecular Function

NAD+ ADP-ribosyltransferase activity | nucleic acid binding | catalytic activity | protein ADP-ribosylase activity | DNA binding | transferase activity, transferring glycosyl groups | organic cyclic compound binding | protein binding | transferase activity, transferring pentosyl groups | transferase activity | heterocyclic compound binding

GO Biological Process

positive regulation of striated muscle cell differentiation | double-strand break repair | regulation of muscle system process | regulation of cell development | positive regulation of striated muscle tissue development | regulation of cardiac muscle cell differentiation | peptidyl-amino acid modification | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | regulation of heart growth | regulation of neuron death | cellular process | extrinsic apoptotic signaling pathway | regulation of cell growth involved in cardiac muscle cell development | regulation of striated muscle tissue development | peptidyl-serine ADP-ribosylation | regulation of cell differentiation | positive regulation of cardiac muscle hypertrophy | positive regulation of muscle cell differentiation | regulation of cellular process | positive regulation of cell growth | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | response to stress | programmed cell death | cellular nitrogen compound metabolic process | protein modification process | macromolecule modification | DNA repair | protein ADP-ribosylase activity | apoptotic process | nitrogen compound metabolic process | cellular response to DNA damage stimulus | positive regulation of muscle organ development | cellular response to stress | positive regulation of cell differentiation | positive regulation of cell growth involved in cardiac muscle cell development | cell communication | base-excision repair | apoptotic signaling pathway | positive regulation of organ growth | protein metabolic process | regulation of cardiac muscle hypertrophy | regulation of growth | protein poly-ADP-ribosylation | regulation of cardiac muscle tissue development | DNA metabolic process | protein ADP-ribosylation | cell surface receptor signaling pathway | metabolic process | positive regulation of cell development | nucleobase-containing compound metabolic process | organic substance metabolic process | cell death | regulation of striated muscle cell differentiation | positive regulation of muscle tissue development | positive regulation of cardiac muscle cell differentiation | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of developmental growth | cellular protein metabolic process | regulation of organ growth | regulation of developmental process | regulation of muscle cell differentiation | regulation of cell growth | cellular protein modification process | positive regulation of heart growth | heterocycle metabolic process | cellular metabolic process | regulation of cell death | positive regulation of cardiac muscle tissue development | negative regulation of cell death | regulation of cellular component organization | signal transduction | regulation of muscle organ development | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular