QuickView for PARP (gene)
- Gene Symbol:
- Parp
D. melanogaster - Full name:
- Poly-(ADP-ribose) polymerase
- Synonyms:
- BEST:LD21673, CG17685, CG17696, CG17718, CG40411, D.PARP, DmelCG40411, Dmel_CG40411, dPARP, LD21673.3prime, Parp, PARP, Parp-1, PARP-1, Parp-2, Parp-e
- Genomic Location:
- Chr 3RHet: 1768646-2027212
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , C. elegans , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | NAD+ ADP-ribosyltransferase activity | cation binding | nucleic acid binding | nucleotide binding | coenzyme binding | catalytic activity | protein ADP-ribosylase activity | DNA binding | transferase activity, transferring glycosyl groups | ion binding | organic cyclic compound binding | protein binding | zinc ion binding | NAD binding | transferase activity, transferring pentosyl groups | transferase activity | histone binding | transition metal ion binding | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of immune response | RNA metabolic process | maintenance of protein location in nucleus | double-strand break repair | nucleus organization | developmental process involved in reproduction | regulation of cellular localization | regulation of localization | morphogenesis of an epithelium | regulation of immune system process | cell differentiation | positive regulation of antimicrobial humoral response | defense response | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | localization | positive regulation of immune effector process | multicellular organismal reproductive process | macromolecule localization | dorsal/ventral axis specification | Cajal body organization | positive regulation of nitrogen compound metabolic process | polytene chromosome puffing | establishment or maintenance of polarity of follicular epithelium | tissue development | gamete generation | regulation of immune response | regulation of cellular process | regulation of metabolic process | positive regulation of antibacterial peptide biosynthetic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | positive regulation of antimicrobial peptide production | response to stimulus | female gamete generation | regulation of cellular protein localization | positive regulation of immune system process | metamorphosis | response to stress | germ cell development | regulation of antimicrobial humoral response | positive regulation of cellular protein localization | cellular nitrogen compound biosynthetic process | protein localization to nucleus | epithelial cell development | regulation of humoral immune response | reproduction | cellular localization | response to temperature stimulus | cellular nitrogen compound metabolic process | maintenance of protein localization in organelle | protein modification process | cellular biosynthetic process | dorsal/ventral pattern formation | macromolecule modification | DNA repair | regulation of nucleic acid-templated transcription | protein ADP-ribosylase activity | dorsal/ventral axis specification, ovarian follicular epithelium | nitrogen compound metabolic process | reproductive process | multicellular organism development | cellular response to DNA damage stimulus | ncRNA transcription | regulation of gene expression | cellular response to stress | cellular response to heat | positive regulation of cellular metabolic process | regulation of protein localization to nucleus | regulation of defense response to bacterium | regulation of nitrogen compound metabolic process | positive regulation of humoral immune response | oogenesis | rRNA transcription | protein localization to organelle | positive regulation of protein localization to nucleus | biosynthetic process | aromatic compound biosynthetic process | regulation of antimicrobial peptide biosynthetic process | rRNA metabolic process | establishment or maintenance of cell polarity | maintenance of protein location | regulation of cellular metabolic process | regulation of RNA metabolic process | positive regulation of defense response to bacterium | multicellular organism reproduction | protein metabolic process | regionalization | axis specification | protein poly-ADP-ribosylation | ovarian follicle cell development | tissue morphogenesis | DNA metabolic process | anatomical structure development | protein ADP-ribosylation | metabolic process | regulation of RNA splicing | regulation of RNA biosynthetic process | cellular protein localization | immune response | heat shock-mediated polytene chromosome puffing | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | nuclear body organization | response to heat | maintenance of protein location in cell | nucleolus organization | transcription, DNA-templated | regulation of antimicrobial peptide production | regulation of transcription, DNA-templated | cell development | protein localization | cellular protein metabolic process | anatomical structure morphogenesis | cellular macromolecule localization | cellular macromolecule biosynthetic process | developmental process | positive regulation of antibacterial peptide production | organelle organization | cellular protein modification process | columnar/cuboidal epithelial cell development | innate immune response | morphogenesis of follicular epithelium | ncRNA metabolic process | epithelial cell differentiation | heterocycle metabolic process | positive regulation of antimicrobial peptide biosynthetic process | positive regulation of metabolic process | chromosome organization | immune system process | cellular metabolic process | regulation of protein localization | sexual reproduction | macromolecule metabolic process | maintenance of location in cell | multicellular organismal process
GO Cellular Component
nuclear euchromatin | chromosome | intracellular membrane-bounded organelle | polytene chromosome | cell | nuclear lumen | nucleolus | intracellular organelle | Cajal body | nuclear body | euchromatin | polytene chromosome puff | nucleoplasm | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular | histone locus body
