QuickView for PCGF6 (gene)

Gene Symbol:

PCGF6 Homo sapiens

Full name:

polycomb group ring finger 6

Synonyms:

MBLR, RNF134, polycomb group RING finger protein 6, Mel18 and Bmi1-like RING finger protein, ring finger protein 134

Genomic Location:

Chr 10: 105052543-105100881

Description:

The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor....

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The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AML1_01 ,  CTCAGGG_MIR125B_MIR125A ,  TGCGCANK_UNKNOWN ,  AACYNNNNTTCCS_UNKNOWN ,  ACCAAAG_MIR9 ,  AML1_Q6 ,  RCGCANGCGY_NRF1_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-9

Cytogenetic Map:

10q24.33

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