QuickView for PDE12;jsessionid=025EF5FECEE11645C1A2480A8FD1E277 (gene)
- Gene Symbol:
- PDE12
Homo sapiens - Full name:
- phosphodiesterase 12
- Synonyms:
- 2'-PDE, 2-PDE, 2',5'-phosphodiesterase 12, 2'-phosphodiesterase, mitochondrial deadenylase
- Genomic Location:
- Chr 3: 57517044-57522720
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
3p14.3
GO Molecular Function
nuclease activity | 3'-5'-exoribonuclease activity | cation binding | poly(A)-specific ribonuclease activity | exoribonuclease activity | hydrolase activity | ribonuclease activity | catalytic activity | hydrolase activity, acting on ester bonds | exoribonuclease activity, producing 5'-phosphomonoesters | ion binding | 3'-5' exonuclease activity | exonuclease activity | metal ion binding
GO Biological Process
RNA metabolic process | negative regulation of phosphorylation | response to cytokine | RNA processing | nuclease activity | 3'-5'-exoribonuclease activity | negative regulation of cellular process | cellular response to interferon-alpha | defense response | positive regulation of viral life cycle | cellular process | organic substance catabolic process | regulation of mitochondrial mRNA stability | mitochondrial mRNA catabolic process | poly(A)-specific ribonuclease activity | negative regulation of cellular metabolic process | regulation of oxidative phosphorylation | regulation of mRNA stability | regulation of cellular process | regulation of metabolic process | catabolic process | positive regulation of viral genome replication | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | negative regulation of nucleotide metabolic process | mRNA catabolic process | exoribonuclease activity | cellular response to interferon-gamma | response to stimulus | response to stress | posttranscriptional regulation of gene expression | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | cellular response to organic cyclic compound | negative regulation of metabolic process | mRNA metabolic process | ribonuclease activity | nuclear-transcribed mRNA catabolic process | nucleobase-containing compound catabolic process | mitochondrial RNA catabolic process | response to nitrogen compound | nitrogen compound metabolic process | negative regulation of phosphate metabolic process | positive regulation of viral process | negative regulation of ATP metabolic process | response to dsRNA | regulation of phosphorylation | regulation of gene expression | RNA catabolic process | regulation of nitrogen compound metabolic process | regulation of RNA stability | response to interferon-alpha | cellular response to cytokine stimulus | exoribonuclease activity, producing 5'-phosphomonoesters | regulation of cellular metabolic process | negative regulation of oxidative phosphorylation | aromatic compound catabolic process | cellular response to dsRNA | regulation of RNA metabolic process | regulation of viral process | response to organic substance | cellular macromolecule catabolic process | metabolic process | 3'-5' exonuclease activity | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | regulation of mRNA catabolic process | RNA phosphodiester bond hydrolysis | gene expression | regulation of ATP metabolic process | regulation of phosphate metabolic process | response to interferon-gamma | RNA phosphodiester bond hydrolysis, exonucleolytic | response to organic cyclic compound | exonuclease activity | innate immune response | heterocycle metabolic process | regulation of generation of precursor metabolites and energy | immune system process | cellular metabolic process | regulation of viral genome replication | mRNA processing | mitochondrial RNA metabolic process | cellular response to organic substance | regulation of cell death | regulation of viral life cycle | negative regulation of cell death | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
mitochondrial matrix | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | membrane-enclosed lumen | intracellular
