Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for PDE4A;jsessionid=16C5FF9F11498D9624F727B3E8F29CFB;jsessionid=2B77BC6C0B56F1E8E4891BC1C2201916 (gene)

Gene Symbol:
Pde4a Rattus norvegicus Rattus norvegicus
Full name:
phosphodiesterase 4A
PHOSA, cAMP-specific 3',5'-cyclic phosphodiesterase 4A, DPDE2, phosphodiesterase 4A, cAMP specific, phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)
Genomic Location:
Chr 8: 20192677-20241557
human homolog catalyzes the hydrolysis of cAMP; activity is inhibited by rolipram
Homo sapiens Mus musculus Macaca mulatta Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):

Transcripts Names
Protein Names

GO Molecular Function

cyclic nucleotide binding | cation binding | cAMP binding | ribonucleotide binding | nucleotide binding | 3',5'-cyclic-AMP phosphodiesterase activity | hydrolase activity | carbohydrate derivative binding | cyclic-nucleotide phosphodiesterase activity | catalytic activity | anion binding | adenyl nucleotide binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | ion binding | organic cyclic compound binding | protein binding | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | metal ion binding | heterocyclic compound binding | 3',5'-cyclic-nucleotide phosphodiesterase activity | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | nucleoside phosphate catabolic process | response to drug | organophosphate catabolic process | cellular process | organic substance catabolic process | nucleotide metabolic process | carbohydrate derivative catabolic process | ribose phosphate metabolic process | ribonucleotide metabolic process | regulation of cellular process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | purine nucleotide metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | regulation of signal transduction | phosphorus metabolic process | cyclic nucleotide metabolic process | nervous system process | organophosphate metabolic process | small molecule metabolic process | cAMP catabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | nucleotide catabolic process | phosphate-containing compound metabolic process | cellular response to drug | cell communication | aromatic compound catabolic process | regulation of cAMP-mediated signaling | cyclic nucleotide catabolic process | cAMP metabolic process | regulation of intracellular signal transduction | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of protein kinase A signaling | sensory perception | organonitrogen compound catabolic process | regulation of cell communication | signaling | sensory perception of chemical stimulus | carbohydrate derivative metabolic process | heterocycle metabolic process | purine ribonucleotide catabolic process | cellular metabolic process | sensory perception of smell | signal transduction | regulation of signaling | purine nucleotide catabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | plasma membrane | perinuclear region of cytoplasm | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane