QuickView for PDE4B;jsessionid=16BA33D194091596FBEEAE45E78F7A6A;jsessionid=B5644001EAA305AC8BFA0690EA55A3F0 (gene)
- Gene Symbol:
- Pde4b
Mus musculus - Full name:
- phosphodiesterase 4B, cAMP specific
- Synonyms:
- Dpde4, R74983, dunce, cAMP-specific 3',5'-cyclic phosphodiesterase 4B
- Genomic Location:
- Chr 4: 101927544-102279867
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
cyclic nucleotide binding | cAMP binding | ribonucleotide binding | nucleotide binding | 3',5'-cyclic-AMP phosphodiesterase activity | hydrolase activity | carbohydrate derivative binding | cyclic-nucleotide phosphodiesterase activity | catalytic activity | ion channel binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | ion binding | organic cyclic compound binding | protein binding | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | purine ribonucleotide binding | tubulin binding | adenyl ribonucleotide binding | gamma-tubulin binding | heterocyclic compound binding | 3',5'-cyclic-nucleotide phosphodiesterase activity | small molecule binding
GO Biological Process
positive regulation of immune response | leukocyte homeostasis | negative regulation of G-protein coupled receptor protein signaling pathway | regulation of muscle system process | cell motility | immune response-regulating signaling pathway | response to lipopolysaccharide | regulation of localization | immune response-regulating cell surface receptor signaling pathway | regulation of immune system process | neutrophil homeostasis | negative regulation of cellular process | immune response-activating cell surface receptor signaling pathway | T cell receptor signaling pathway | response to drug | cellular response to epinephrine stimulus | cellular process | localization | negative regulation of signaling | negative regulation of relaxation of muscle | granulocyte chemotaxis | regulation of immune response | regulation of cellular process | cellular response to lipid | regulation of relaxation of muscle | cellular response to molecule of bacterial origin | positive regulation of interferon-gamma production | cellular response to organonitrogen compound | smooth muscle contraction | muscle contraction | response to stimulus | neutrophil chemotaxis | positive regulation of immune system process | regulation of blood circulation | regulation of cardiac muscle cell contraction | regulation of high voltage-gated calcium channel activity | response to molecule of bacterial origin | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway | immune response-activating signal transduction | cellular response to organic cyclic compound | cell chemotaxis | myeloid cell homeostasis | leukocyte migration | locomotion | response to nitrogen compound | response to external biotic stimulus | regulation of signal transduction | cell migration | regulation of muscle contraction | response to lipid | response to epinephrine | negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | regulation of cellular component movement | negative regulation of relaxation of cardiac muscle | homeostasis of number of cells | regulation of calcium ion transmembrane transport | regulation of voltage-gated calcium channel activity | regulation of heart contraction | cellular response to drug | regulation of striated muscle contraction | response to bacterium | regulation of relaxation of cardiac muscle | cell communication | response to catecholamine | regulation of cardiac muscle contraction | regulation of cAMP-mediated signaling | leukocyte chemotaxis | homeostatic process | response to monoamine | activation of immune response | response to organic substance | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | cell surface receptor signaling pathway | negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of ion transmembrane transport | antigen receptor-mediated signaling pathway | positive regulation of cytokine production | regulation of cell communication | negative regulation of signal transduction | signaling | response to organic cyclic compound | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | regulation of cytokine production | response to biotic stimulus | regulation of ion transport | regulation of G-protein coupled receptor protein signaling pathway | negative regulation of cAMP-mediated signaling | regulation of calcium ion transport | positive regulation of interleukin-2 production | regulation of transport | regulation of cation channel activity | response to organonitrogen compound | regulation of actin filament-based process | regulation of calcium ion transmembrane transporter activity | regulation of interferon-gamma production | immune system process | cellular response to organic substance | neutrophil migration | chemotaxis | muscle system process | response to other organism | cellular response to catecholamine stimulus | signal transduction | regulation of signaling | cellular response to lipopolysaccharide | multicellular organismal process
GO Cellular Component
supramolecular fiber | dendritic spine | exocytic vesicle | integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | sarcomere | microtubule organizing center | cytoplasmic vesicle | voltage-gated calcium channel complex | cell | plasma membrane protein complex | intrinsic component of membrane | myofibril | cytoplasm | intracellular organelle | dendritic tree | contractile fiber | presynapse | centrosome | protein-containing complex | cell projection | secretory vesicle | endomembrane system | neuron spine | postsynapse | plasma membrane | vesicle | transport vesicle | perinuclear region of cytoplasm | postsynaptic density | microtubule cytoskeleton | asymmetric synapse | synaptic vesicle | calcium channel complex | gamma-tubulin complex | membrane-bounded organelle | nucleus | organelle | postsynaptic specialization | I band | cell periphery | excitatory synapse | transmembrane transporter complex | cation channel complex | ion channel complex | Z disc | cytosol | intracellular vesicle | cytoskeleton | intracellular | membrane | supramolecular complex
