QuickView for PDE4D;jsessionid=92271347B9F0B06840E10B1EA524794E (gene)

Gene Symbol:

PDE4D Homo sapiens

Full name:

phosphodiesterase 4D

Synonyms:

ACRDYS2, DPDE3, HSPDE4D, PDE43, PDE4DN2, STRK1, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, cAMP-specific phosphodiesterase PDE4D6, phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila), testicular tissue protein Li 136

Genomic Location:

Chr 5: 58300622-59225378

Description:

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode ...

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This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  PR_Q2 ,  GTATTAT_MIR3693P ,  OCT1_05 ,  GTGCCAT_MIR183 ,  SMTTTTGT_UNKNOWN ,  HNF3ALPHA_Q6 ,  GTGTTGA_MIR505 ,  STAT4_01 ,  TGANTCA_AP1_C ,  CEBPA_01 ,  OCT1_B ,  STAT1_02 ,  TTANTCA_UNKNOWN ,  FOXJ2_02 ,  RYTTCCTG_ETS2_B ,  NFAT_Q6 ,  OCT1_01 ,  ATGTCAC_MIR489 ,  FOXO4_01 ,  OCT_Q6 ,  SMAD3_Q6 ,  STAT6_02 ,  AACTGAC_MIR223 ,  CIZ_01 ,  ATF4_Q2 ,  EVI1_04 ,  TTTGTAG_MIR520D ,  YNTTTNNNANGCARM_UNKNOWN ,  CEBP_Q2_01 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  GTACTGT_MIR101 ,  ATGTACA_MIR493 ,  STAT1_03 ,  GCCATNTTG_YY1_Q6 ,  OCT1_Q5_01 ,  OCT_C ,  TATCTGG_MIR488 ,  CREBP1_Q2 ,  GGTGTGT_MIR329 ,  CEBP_Q2 ,  OCT1_Q6 ,  TGTATGA_MIR4853P ,  LEF1_Q6 ,  CATTTCA_MIR203 ,  CAGGTA_AREB6_01 ,  CAGNYGKNAAA_UNKNOWN ,  YY1_01 ,  TGCGCANK_UNKNOWN ,  GTCTTCC_MIR7 ,  GTTTGTT_MIR495 ,  ATGTTAA_MIR302C ,  GTATGAT_MIR154_MIR487 ,  GACAATC_MIR219 ,  CEBPB_02 ,  TGTTTGY_HNF3_Q6 ,  ATACTGT_MIR144 ,  NRF2_Q4 ,  AP1_Q4 ,  OCT1_06 ,  YCATTAA_UNKNOWN ,  GFI1_01 ,  HMGIY_Q6 ,  HLF_01 ,  OCT1_02 ,  TTGTTT_FOXO4_01 ,  ATF1_Q6 ,  CEBP_C ,  GATA4_Q3 ,  WWTAAGGC_UNKNOWN ,  IRF7_01 ,  CTGCAGY_UNKNOWN ,  KMCATNNWGGA_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  CRX_Q4 ,  HNF1_Q6 ,  PAX4_01 ,  TATTATA_MIR374 ,  ACACTGG_MIR199A_MIR199B ,  TGASTMAGC_NFE2_01 ,  TCF11_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-18 ,  Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-199 ,  Predicted Gene Targets for miR-208 ,  Predicted Gene Targets for miR-219 ,  Predicted Gene Targets for miR-223 ,  Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-329 ,  Predicted Gene Targets for miR-33 ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-542-3p ,  Predicted Gene Targets for miR-7 ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-151 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-375 ,  Predicted Gene Targets for miR-409-5p ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-485-3p ,  Predicted Gene Targets for miR-488 ,  Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-496 ,  Predicted Gene Targets for miR-499 ,  Predicted Gene Targets for miR-505 ,  Predicted Gene Targets for miR-543 ,  Predicted Gene Targets for miR-378

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Cytogenetic Map:

5q11.2-q12.1

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