QuickView for PDE6G (gene)
- Gene Symbol:
- PDE6G
Homo sapiens - Full name:
- phosphodiesterase 6G
- Synonyms:
- PDEG, RP57, retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma, phosphodiesterase 6G, cGMP-specific, rod, gamma, rod cG-PDE G
- Genomic Location:
- Chr 17: 77227894-77234038
- Description:
-
This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to r...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Danio rerio , Pan troglodytes
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
17q25.3
GO Molecular Function
guanyl ribonucleotide binding | cyclic nucleotide binding | ribonucleotide binding | nucleotide binding | enzyme inhibitor activity | hydrolase activity | spectrin binding | carbohydrate derivative binding | cyclic-nucleotide phosphodiesterase activity | molecular function regulator | catalytic activity | cytoskeletal protein binding | anion binding | cGMP binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | 3',5'-cyclic-GMP phosphodiesterase activity | ion binding | organic cyclic compound binding | protein binding | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | purine ribonucleotide binding | enzyme regulator activity | heterocyclic compound binding | 3',5'-cyclic-nucleotide phosphodiesterase activity | guanyl nucleotide binding | small molecule binding
GO Biological Process
regulation of MAP kinase activity | positive regulation of phosphate metabolic process | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | response to stimulus | enzyme inhibitor activity | positive regulation of protein metabolic process | positive regulation of protein serine/threonine kinase activity | activation of protein kinase activity | positive regulation of ERBB signaling pathway | molecular function regulator | regulation of signal transduction | negative regulation of catalytic activity | regulation of MAPK cascade | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | nervous system process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | regulation of cellular protein metabolic process | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | positive regulation of molecular function | activation of MAPK activity | positive regulation of protein modification process | regulation of kinase activity | regulation of intracellular signal transduction | visual perception | regulation of epidermal growth factor receptor signaling pathway | sensory perception of light stimulus | positive regulation of G-protein coupled receptor protein signaling pathway | positive regulation of kinase activity | regulation of phosphate metabolic process | positive regulation of MAPK cascade | sensory perception | regulation of cell communication | negative regulation of molecular function | regulation of ERBB signaling pathway | positive regulation of phosphorylation | enzyme regulator activity | positive regulation of epidermal growth factor receptor signaling pathway | positive regulation of MAP kinase activity | regulation of G-protein coupled receptor protein signaling pathway | regulation of rhodopsin mediated signaling pathway | positive regulation of metabolic process | positive regulation of signaling | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
non-motile cilium | neuron projection | ciliary membrane | organelle membrane | cell projection membrane | cell | cell projection | plasma membrane | cilium | photoreceptor outer segment | photoreceptor disc membrane | 9+0 non-motile cilium | photoreceptor cell cilium | membrane-bounded organelle | organelle | cell periphery | membrane
