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QuickView for PDE7A (gene)


Gene Symbol:
PDE7A Homo sapiens Homo sapiens
Full name:
phosphodiesterase 7A
Synonyms:
HCP1, PDE7, high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, TM22, phosphodiesterase isozyme 7
Genomic Location:
Chr 8: 66793867-66916297
Description:
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in m...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 8
8q13.1





GO Molecular Function

cation binding | 3',5'-cyclic-AMP phosphodiesterase activity | hydrolase activity | cyclic-nucleotide phosphodiesterase activity | catalytic activity | hydrolase activity, acting on ester bonds | ion binding | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | metal ion binding | 3',5'-cyclic-nucleotide phosphodiesterase activity

GO Biological Process

purine ribonucleotide metabolic process | nucleoside phosphate catabolic process | organophosphate catabolic process | cellular process | organic substance catabolic process | nucleotide metabolic process | carbohydrate derivative catabolic process | ribose phosphate metabolic process | ribonucleotide metabolic process | regulation of cellular process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | purine nucleotide metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | G-protein coupled receptor signaling pathway | cellular biosynthetic process | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | phosphorus metabolic process | cyclic nucleotide metabolic process | organophosphate metabolic process | small molecule metabolic process | cAMP catabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | nucleotide catabolic process | phosphate-containing compound metabolic process | cell communication | aromatic compound catabolic process | cyclic nucleotide catabolic process | cAMP metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | organonitrogen compound catabolic process | signaling | carbohydrate derivative metabolic process | heterocycle metabolic process | purine ribonucleotide catabolic process | cellular metabolic process | signal transduction | purine nucleotide catabolic process

GO Cellular Component

cell | cytoplasm | cytosol | intracellular