QuickView for PDLIM1;jsessionid=88BFBC24181686B5F95C308A74B592B1 (gene)
- Gene Symbol:
- PDLIM1
Homo sapiens - Full name:
- PDZ and LIM domain 1
- Synonyms:
- CLIM1, CLP-36, CLP36, HEL-S-112, hCLIM1, PDZ and LIM domain protein 1, LIM domain protein CLP-36, carboxyl terminal LIM domain protein 1, elfin, epididymis secretory protein Li 112
- Genomic Location:
- Chr 10: 96987319-97040771
- Description:
-
This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to t...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
HNF1_01 , RSRFC4_01 , RSRFC4_Q2 , MEIS1BHOXA9_01 , AMEF2_Q6 , TAAWWATAG_RSRFC4_Q2 , STAT5B_01 , HMEF2_Q6 , STAT_01 , GFI1_01
- Cytogenetic Map:
-
10q23.33
GO Molecular Function
cadherin binding | cation binding | cadherin binding involved in cell-cell adhesion | cell-cell adhesion mediator activity | ion binding | cell adhesion molecule binding | transcription coactivator activity | protein binding | cell adhesion mediator activity | transcription coregulator activity | metal ion binding
GO Biological Process
positive regulation of macromolecule biosynthetic process | positive regulation of cellular biosynthetic process | cadherin binding involved in cell-cell adhesion | response to hypoxia | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | cell-cell adhesion mediator activity | response to stimulus | response to stress | positive regulation of RNA biosynthetic process | regulation of nucleic acid-templated transcription | response to oxygen levels | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | response to oxidative stress | regulation of cellular metabolic process | transcription coactivator activity | regulation of RNA metabolic process | regulation of RNA biosynthetic process | cell adhesion | cell-cell adhesion | cell adhesion mediator activity | regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | transcription coregulator activity | positive regulation of metabolic process
GO Cellular Component
supramolecular fiber | adherens junction | sarcomere | focal adhesion | cell | transcription factor complex | myofibril | cytoplasm | cell-substrate junction | intracellular organelle | contractile fiber | cell-cell adherens junction | cell-cell junction | protein-containing complex | organelle | I band | cell-substrate adherens junction | Z disc | cytoskeleton | intracellular | cell junction | supramolecular complex
