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QuickView for PGAM1 (gene)


Gene Symbol:
PGAM1 Homo sapiens Homo sapiens
Full name:
phosphoglycerate mutase 1
Synonyms:
HEL-S-35, PGAM-B, PGAMA, phosphoglycerate mutase 1, BPG-dependent PGAM 1, epididymis secretory protein Li 35, phosphoglycerate mutase 1 (brain), phosphoglycerate mutase A, nonmuscle form, phosphoglycerate mutase isozyme B
Genomic Location:
Chr 10: 99176017-99183188
Description:
The protein encoded by this gene is a mutase that catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Two transcript variants encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 10
10q24.1


Transcripts Names
NM_002629
NM_001317079
Protein Names
Q9BWC0
P18669
B7Z9E5
Q6FHU2



GO Molecular Function

kinase binding | protein kinase binding | isomerase activity | enzyme binding | hydrolase activity | intramolecular transferase activity, phosphotransferases | catalytic activity | bisphosphoglycerate mutase activity | protein binding | intramolecular transferase activity | phosphoglycerate mutase activity

GO Biological Process

purine ribonucleotide metabolic process | purine ribonucleoside monophosphate biosynthetic process | exocytosis | nucleoside phosphate catabolic process | neutrophil activation | glycolytic process | regulation of carbohydrate metabolic process | establishment of localization | glucose metabolic process | nicotinamide nucleotide biosynthetic process | generation of precursor metabolites and energy | organophosphate catabolic process | cellular process | secretion | organic substance catabolic process | leukocyte degranulation | localization | regulation of glycolytic process | nucleotide metabolic process | NADH regeneration | ribose phosphate metabolic process | purine nucleotide biosynthetic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | carbohydrate catabolic process | regulation of cellular process | leukocyte activation | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | purine nucleotide metabolic process | monocarboxylic acid metabolic process | neutrophil degranulation | leukocyte activation involved in immune response | cellular nitrogen compound biosynthetic process | secretion by cell | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cofactor metabolic process | cellular biosynthetic process | nucleobase-containing compound catabolic process | nucleotide biosynthetic process | NADH metabolic process | ATP biosynthetic process | nitrogen compound metabolic process | coenzyme biosynthetic process | phosphorus metabolic process | ribonucleoside monophosphate biosynthetic process | leukocyte mediated immunity | regulation of phosphorylation | NAD biosynthetic process | organophosphate metabolic process | hexose biosynthetic process | nucleotide phosphorylation | cofactor biosynthetic process | regulation of nitrogen compound metabolic process | monosaccharide metabolic process | small molecule metabolic process | vesicle-mediated transport | nucleobase-containing small molecule metabolic process | carbohydrate biosynthetic process | biosynthetic process | pyruvate metabolic process | aromatic compound biosynthetic process | phosphorylation | purine ribonucleotide biosynthetic process | regulated exocytosis | carbohydrate metabolic process | nucleotide catabolic process | nucleoside triphosphate biosynthetic process | phosphate-containing compound metabolic process | regulation of cellular metabolic process | cell activation involved in immune response | myeloid cell activation involved in immune response | aromatic compound catabolic process | neutrophil activation involved in immune response | drug metabolic process | carboxylic acid metabolic process | pyridine nucleotide biosynthetic process | glycolytic process through glucose-6-phosphate | nucleoside diphosphate metabolic process | metabolic process | hexose metabolic process | oxidation-reduction process | gluconeogenesis | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | glycolytic process through fructose-6-phosphate | ATP generation from ADP | regulation of ATP metabolic process | regulation of phosphate metabolic process | cell activation | respiratory burst | pyruvate biosynthetic process | ADP metabolic process | ribose phosphate biosynthetic process | organic acid metabolic process | glucose catabolic process | nicotinamide nucleotide metabolic process | NAD metabolic process | carbohydrate derivative metabolic process | neutrophil mediated immunity | canonical glycolysis | heterocycle metabolic process | regulation of generation of precursor metabolites and energy | immune system process | cellular metabolic process | ATP metabolic process | nucleoside diphosphate phosphorylation | regulation of pentose-phosphate shunt | regulation of NADP metabolic process | nucleoside monophosphate biosynthetic process | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | ficolin-1-rich granule lumen | secretory vesicle | endomembrane system | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | membrane-enclosed lumen | secretory granule lumen | cytosol | intracellular vesicle | intracellular | myelin sheath | membrane | vesicle lumen