QuickView for PIP3 (gene)
- Gene Symbol:
- MEC3
Saccharomyces cerevisiae - Full name:
- DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric complex (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded onto partial duplex DNA by a clamp loader complex; homolog of human and S. pombe Hus1
- Synonyms:
- MEC3, PIP3, PSO9, YLR288C
- Genomic Location:
- Chr XII: 713482-714906
- External Links:
- Entrez Gene
GO Molecular Function
nucleic acid binding | DNA binding | organic cyclic compound binding | heterocyclic compound binding
GO Biological Process
double-strand break repair | intra-S DNA damage checkpoint | regulation of cell cycle process | telomere maintenance | meiotic DNA integrity checkpoint | chromatin silencing at telomere | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cellular process | regulation of gene expression, epigenetic | chromatin organization | mitotic DNA integrity checkpoint | negative regulation of nucleic acid-templated transcription | regulation of cell cycle | negative regulation of cellular metabolic process | anatomical structure homeostasis | regulation of cellular process | gene silencing | regulation of metabolic process | organic cyclic compound metabolic process | DNA replication checkpoint | cellular aromatic compound metabolic process | regulation of G2/M transition of mitotic cell cycle | cellular component organization | response to stimulus | regulation of mitotic cell cycle phase transition | response to stress | negative regulation of G2/M transition of mitotic cell cycle | regulation of cell cycle phase transition | reproduction | cellular nitrogen compound metabolic process | telomere organization | mitotic DNA replication checkpoint | negative regulation of metabolic process | DNA recombination | DNA repair | regulation of nucleic acid-templated transcription | regulation of cell cycle G2/M phase transition | nitrogen compound metabolic process | reproductive process | negative regulation of mitotic cell cycle phase transition | double-strand break repair via homologous recombination | mitotic DNA damage checkpoint | negative regulation of cell cycle G2/M phase transition | cellular response to DNA damage stimulus | regulation of gene expression | cellular response to stress | cell cycle | negative regulation of gene expression, epigenetic | regulation of nitrogen compound metabolic process | meiotic cell cycle checkpoint | regulation of cellular metabolic process | homeostatic process | regulation of RNA metabolic process | regulation of mitotic cell cycle | mitotic G2/M transition checkpoint | DNA metabolic process | mitotic cell cycle | metabolic process | nucleotide-excision repair | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | mitotic recombination | telomere maintenance via recombination | negative regulation of cell cycle | meiotic cell cycle | regulation of transcription, DNA-templated | recombinational repair | organelle organization | heterocycle metabolic process | chromosome organization | chromatin silencing | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | DNA damage checkpoint | cell cycle checkpoint | macromolecule metabolic process
GO Cellular Component
condensed nuclear chromosome | site of DNA damage | chromosome | intracellular membrane-bounded organelle | cell | checkpoint clamp complex | nuclear lumen | intracellular organelle | protein-containing complex | nuclear chromosome | chromosome, telomeric region | site of double-strand break | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | condensed chromosome
