QuickView for PLCB3;jsessionid=4F3E745D2C96C6B4BDABA79C73C35308 (gene)
- Gene Symbol:
- PLCB3
Homo sapiens - Full name:
- phospholipase C beta 3
- Synonyms:
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, PLC beta 3, phosphoinositide phospholipase C-beta-3, phospholipase C, beta 3 (phosphatidylinositol-specific)
- Genomic Location:
- Chr 11: 63775698-63791604
- Description:
-
This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
11q13.1
GO Molecular Function
cadherin binding | cation binding | phospholipase activity | hydrolase activity | catalytic activity | hydrolase activity, acting on ester bonds | ion binding | lipase activity | cell adhesion molecule binding | protein binding | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | phosphatidylinositol phospholipase C activity | calcium ion binding | phospholipase C activity | calmodulin binding | metal ion binding
GO Biological Process
intracellular signal transduction | polyol metabolic process | cellular process | organic substance catabolic process | regulation of cellular process | catabolic process | response to stimulus | alcohol metabolic process | blood circulation | G-protein coupled receptor signaling pathway | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | organic hydroxy compound metabolic process | Wnt signaling pathway | phosphorus metabolic process | lipid metabolic process | regulation of blood pressure | organophosphate metabolic process | regulation of systemic arterial blood pressure | small molecule metabolic process | non-canonical Wnt signaling pathway | phosphate-containing compound metabolic process | cell communication | Wnt signaling pathway, calcium modulating pathway | cell surface receptor signaling pathway | metabolic process | lipid catabolic process | organic substance metabolic process | signaling | cellular metabolic process | inositol phosphate metabolic process | signal transduction | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular | membrane
