QuickView for PLCH1;jsessionid=4F3E745D2C96C6B4BDABA79C73C35308 (gene)

Gene Symbol:

PLCH1 Homo sapiens

Full name:

phospholipase C eta 1

Synonyms:

PLCL3, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1, PLC eta 1, PLC-L3, phosphoinositide phospholipase C-eta-1, phospholipase C-eta1a, phospholipase C-eta1b, phospholipase C-like 3, phospholipase C-like protein 3

Genomic Location:

Chr 3: 156680365-156796861

Description:

PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).

PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTTTGTT_MIR495 ,  TTGCCAA_MIR182

Cytogenetic Map:

3q25.31

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