QuickView for PLD2 (gene)

Gene Symbol:

PLD2 Homo sapiens

Full name:

phospholipase D2

Synonyms:

PLD1C, phospholipase D2, choline phosphatase 2, phosphatidylcholine-hydrolyzing phospholipase D2

Genomic Location:

Chr 17: 4657378-4673694

Description:

The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle contr...

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The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CATTTCA_MIR203

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-203

Cytogenetic Map:

17p13.2

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