QuickView for PMP2 (gene)

Gene Symbol:

PMP2 Homo sapiens

Full name:

peripheral myelin protein 2

Synonyms:

FABP8, M-FABP, MP2, P2, myelin P2 protein

Genomic Location:

Chr 8: 82515116-82522274

Description:

The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy.

The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CTTTGA_LEF1_Q2 ,  TATAAA_TATA_01 ,  TGCCAAR_NF1_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-503 ,  Predicted Gene Targets for miR-493-5p

Cytogenetic Map:

8q21.13

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