QuickView for POLA2 (gene)
- Gene Symbol:
- POLA2
Homo sapiens - Full name:
- DNA polymerase alpha 2, accessory subunit
- Synonyms:
- DNA polymerase alpha subunit B, DNA polymerase alpha 70 kDa subunit, polymerase (DNA directed), alpha 2 (70kD subunit), polymerase (DNA directed), alpha 2, accessory subunit, polymerase (DNA) alpha 2, accessory subunit, polymerase (DNA-directed), alpha (70kD)
- Genomic Location:
- Chr 11: 64786006-64821664
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
E2F1_Q4_01 , E2F1_Q4 , E2F_Q6 , E2F1_Q6_01 , E2F_Q4 , E2F_03 , NRF1_Q6 , E2F_Q4_01 , E2F1DP1RB_01 , RCGCANGCGY_NRF1_Q6
- Cytogenetic Map:
-
11q13.1
GO Molecular Function
DNA-directed DNA polymerase activity | nucleic acid binding | DNA polymerase activity | nucleotidyltransferase activity | catalytic activity | DNA binding | protein heterodimerization activity | organic cyclic compound binding | protein binding | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | transferase activity | heterocyclic compound binding
GO Biological Process
telomere maintenance | establishment of localization | intracellular transport | cellular process | localization | cellular homeostasis | protein transport | cell cycle DNA replication | DNA-directed DNA polymerase activity | macromolecule localization | establishment of localization in cell | anatomical structure homeostasis | protein import into nucleus | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | DNA-dependent DNA replication | cellular component organization | DNA replication initiation | intracellular protein transport | cellular nitrogen compound biosynthetic process | protein localization to nucleus | DNA polymerase activity | cellular localization | cellular nitrogen compound metabolic process | telomere organization | cell cycle G1/S phase transition | cellular biosynthetic process | nitrogen compound metabolic process | protein import into nucleus, translocation | DNA biosynthetic process | organic substance transport | cell cycle | peptide transport | protein localization to organelle | import into nucleus | telomere maintenance via semi-conservative replication | biosynthetic process | aromatic compound biosynthetic process | mitotic cell cycle phase transition | protein import | homeostatic process | G1/S transition of mitotic cell cycle | DNA metabolic process | establishment of protein localization to organelle | mitotic cell cycle | metabolic process | cellular protein localization | amide transport | nucleobase-containing compound metabolic process | organic substance metabolic process | nuclear transport | establishment of protein localization | protein localization | cellular macromolecule localization | cellular macromolecule biosynthetic process | nucleocytoplasmic transport | nuclear DNA replication | organelle organization | cell cycle phase transition | heterocycle metabolic process | chromosome organization | cellular metabolic process | DNA replication | macromolecule metabolic process
GO Cellular Component
alpha DNA polymerase:primase complex | nuclear replisome | chromosome | intracellular membrane-bounded organelle | catalytic complex | nuclear replication fork | cell | nuclear lumen | replication fork | cytoplasm | intracellular organelle | protein-containing complex | protein-DNA complex | nucleoplasm | nuclear chromosome | transferase complex | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | replisome | RNA polymerase complex | membrane-enclosed lumen | cytosol | intracellular
