QuickView for POLB (gene)

Gene Symbol:

POLB Homo sapiens

Full name:

DNA polymerase beta

Synonyms:

DNA polymerase beta, DNA pol beta, DNA polymerase beta subunit, polymerase (DNA directed), beta, polymerase (DNA) beta

Genomic Location:

Chr 8: 42315187-42348470

Description:

The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has...

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The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CGTSACG_PAX3_B ,  CATTGTYY_SOX9_B1 ,  SOX9_B1 ,  GTGACGY_E4F1_Q6 ,  CREB_02 ,  GGGCGGR_SP1_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-376c

Cytogenetic Map:

8p11.21

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