QuickView for POLD1 (gene)

Gene Symbol:

POLD1 Homo sapiens

Full name:

DNA polymerase delta 1, catalytic subunit

Synonyms:

CDC2, CRCS10, MDPL, POLD, DNA polymerase delta catalytic subunit, CDC2 homolog, DNA polymerase subunit delta p125, polymerase (DNA directed), delta 1, catalytic subunit 125kDa, polymerase (DNA) delta 1, catalytic subunit

Genomic Location:

Chr 19: 55579405-55613083

Description:

This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chr...

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This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Pan troglodytes ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E2F4DP1_01 ,  VDR_Q6 ,  E2F_Q6_01 ,  COUP_01 ,  E2F_Q6 ,  E2F_Q4 ,  E2F1DP2_01 ,  E2F_03 ,  E2F1DP1_01 ,  E2F1DP1RB_01 ,  E2F_02 ,  E2F1_Q3 ,  E2F4DP2_01 ,  KTGGYRSGAA_UNKNOWN ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01

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Cytogenetic Map:

19q13.33

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