Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for PPAR (gene)


Gene Symbol:
Ppara Rattus norvegicus Rattus norvegicus
Full name:
peroxisome proliferator activated receptor alpha
Synonyms:
PPAR, peroxisome proliferator-activated receptor alpha, PPAR-alpha, nuclear receptor subfamily 1 group C member 1
Genomic Location:
Chr 7: 123729774-123807090
Description:
nuclear steroid receptor; heterodimerizes with retinoid-X receptor (RXR), and binds to peroxisome proliferator response elements (PPREs) to initiate the transcriptional regulation of target genes
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

sequence-specific DNA binding | fatty acid binding | transcription factor activity, transcription factor binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | nuclear receptor activity | cation binding | repressing transcription factor binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | transcription factor activity, RNA polymerase II transcription factor binding | proximal promoter sequence-specific DNA binding | carboxylic acid binding | enzyme binding | nucleic acid binding | protein-containing complex binding | lipid binding | transcription coactivator binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | steroid hormone receptor activity | protein domain specific binding | NFAT protein binding | anion binding | RNA polymerase II repressing transcription factor binding | RNA polymerase II regulatory region DNA binding | ubiquitin conjugating enzyme binding | DNA binding | MDM2/MDM4 family protein binding | signaling receptor activity | sequence-specific double-stranded DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | ion binding | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | transcriptional activator activity, RNA polymerase II transcription factor binding | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | nuclear receptor transcription coactivator activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | ubiquitin-like protein conjugating enzyme binding | transition metal ion binding | drug binding | phosphatase binding | transcription cofactor binding | transcription coregulator activity | organic acid binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | response to extracellular stimulus | regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | response to nutrient levels | negative regulation of sequestering of triglyceride | regulation of localization | regulation of carbohydrate metabolic process | response to hormone | negative regulation of neuron death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | positive regulation of fatty acid oxidation | negative regulation of leukocyte cell-cell adhesion | negative regulation of RNA biosynthetic process | cell differentiation | response to drug | regulation of lipid transport | hormone-mediated signaling pathway | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | negative regulation of inflammatory response | nuclear receptor activity | circadian regulation of gene expression | regulation of glycolytic process | odontogenesis | transcription factor activity, direct ligand regulated sequence-specific DNA binding | negative regulation of nucleic acid-templated transcription | response to hypoxia | tooth mineralization | positive regulation of nitrogen compound metabolic process | regulation of appetite | negative regulation of cholesterol storage | transcription factor activity, RNA polymerase II transcription factor binding | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | regulation of binding | regulation of cell differentiation | negative regulation of receptor biosynthetic process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | negative regulation of appetite | cellular aromatic compound metabolic process | behavioral response to nicotine | cellular lipid metabolic process | response to stimulus | monocarboxylic acid metabolic process | regulation of macrophage derived foam cell differentiation | negative regulation of cell adhesion | response to stress | cellular nitrogen compound biosynthetic process | response to peptide | circadian rhythm | regulation of transcription regulatory region DNA binding | rhythmic process | cellular nitrogen compound metabolic process | regulation of DNA binding | cellular response to organic cyclic compound | blood circulation | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | steroid hormone receptor activity | steroid hormone mediated signaling pathway | regulation of cell adhesion | cellular biosynthetic process | regulation of lipid storage | negative regulation of blood pressure | regulation of nucleic acid-templated transcription | response to nitrogen compound | cellular response to hormone stimulus | response to nicotine | system development | response to oxygen levels | nitrogen compound metabolic process | multicellular organism development | lipid metabolic process | regulation of phosphorylation | positive regulation of gluconeogenesis | regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter | wound healing | regulation of gene expression | response to lipid | regulation of response to food | regulation of blood pressure | positive regulation of cellular metabolic process | negative regulation of lipid storage | animal organ morphogenesis | regulation of pri-miRNA transcription by RNA polymerase II | amelogenesis | regulation of nitrogen compound metabolic process | small molecule metabolic process | negative regulation of DNA binding | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of binding | regulation of fatty acid metabolic process | biosynthetic process | aromatic compound biosynthetic process | negative regulation of transcription regulatory region DNA binding | epidermis development | response to toxic substance | regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter | negative regulation of cell-cell adhesion | cell communication | negative regulation of protein binding | regulation of cellular metabolic process | lipoprotein metabolic process | odontogenesis of dentin-containing tooth | heart development | regulation of sequestering of triglyceride | transcription coactivator activity | regulation of RNA metabolic process | carboxylic acid metabolic process | transcriptional activator activity, RNA polymerase II transcription factor binding | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | protein metabolic process | DNA-binding transcription factor activity | negative regulation of response to food | response to organic substance | response to wounding | positive regulation of fatty acid metabolic process | response to insulin | anatomical structure development | regulation of glucose metabolic process | metabolic process | regulation of receptor biosynthetic process | positive regulation of glucose metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nuclear receptor transcription coactivator activity | behavior | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | regulation of fatty acid oxidation | regulation of ATP metabolic process | regulation of phosphate metabolic process | biomineral tissue development | cellular response to steroid hormone stimulus | fatty acid metabolic process | transcription, DNA-templated | intracellular receptor signaling pathway | anatomical structure formation involved in morphogenesis | adult behavior | positive regulation of carbohydrate metabolic process | negative regulation of macrophage derived foam cell differentiation | negative regulation of molecular function | signaling | regulation of transcription, DNA-templated | regulation of protein binding | response to organic cyclic compound | organic acid metabolic process | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of circadian rhythm | regulation of cellular ketone metabolic process | regulation of developmental process | developmental process | negative regulation of transcription by RNA polymerase II | regulation of transport | positive regulation of transcription, DNA-templated | regulation of cell-cell adhesion | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | transcription coregulator activity | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | regulation of gluconeogenesis | regulation of generation of precursor metabolites and energy | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | cellular metabolic process | cellular response to organic substance | enamel mineralization | regulation of cell death | response to steroid hormone | negative regulation of cell death | circulatory system development | regulation of inflammatory response | negative regulation of pri-miRNA transcription by RNA polymerase II | negative regulation of cell differentiation | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular