QuickView for PPIF;jsessionid=64EE3FB6B9C8693E79AC5B369EF2B336 (gene)

Gene Symbol:

PPIF Homo sapiens

Full name:

peptidylprolyl isomerase F

Synonyms:

CYP3, CyP-M, Cyp-D, CypD, peptidyl-prolyl cis-trans isomerase F, mitochondrial, PPIase F, cyclophilin 3, cyclophilin D, cyclophilin F, mitochondrial cyclophilin, peptidyl-prolyl cis-trans isomerase, mitochondrial, rotamase F

Genomic Location:

Chr 10: 80777226-80785096

Description:

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Act...

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The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MYOD_Q6_01 ,  RYTTCCTG_ETS2_B ,  GTGCCTT_MIR506 ,  AATGTGA_MIR23A_MIR23B

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-124a

Cytogenetic Map:

10q22.3

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