QuickView for PRAS40 (gene)

Gene Symbol:

AKT1S1 Homo sapiens

Full name:

AKT1 substrate 1

Synonyms:

Lobe, PRAS40, proline-rich AKT1 substrate 1, 40 kDa proline-rich AKT substrate, AKT1 substrate 1 (proline rich)

Genomic Location:

Chr 19: 55064108-55072456

Description:

AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).

AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

FOXO1_02 ,  RTAAACA_FREAC2_01 ,  STAT4_01 ,  TGANTCA_AP1_C ,  RYTTCCTG_ETS2_B ,  YATGNWAAT_OCT_C ,  STAT6_02 ,  GGAMTNNNNNTCCY_UNKNOWN ,  TGAGATT_MIR216 ,  AP1_Q6 ,  NFKAPPAB65_01 ,  NFE2_01 ,  AP1_Q6_01 ,  FOXO3_01 ,  FREAC3_01 ,  AP1FJ_Q2 ,  TGCCTTA_MIR124A ,  GGGCGGR_SP1_Q6 ,  GGCNRNWCTTYS_UNKNOWN ,  GCGNNANTTCC_UNKNOWN ,  FOXO1_01 ,  AP1_Q4 ,  GTGCCTT_MIR506 ,  CETS1P54_01 ,  ELK1_01 ,  TTGTTT_FOXO4_01 ,  SCGGAAGY_ELK1_02 ,  YY1_02 ,  NRF2_01 ,  PAX_Q6 ,  CREL_01 ,  AP1_Q2 ,  RCGCANGCGY_NRF1_Q6 ,  ELK1_02 ,  ELF1_Q6 ,  FOXO4_02 ,  ACACTAC_MIR1423P ,  TCF11MAFG_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-142-3p ,  Predicted Gene Targets for miR-216 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u

Cytogenetic Map:

19q13.33

search → result