QuickView for PRDX1 (gene)

Gene Symbol:

PRDX1 Homo sapiens

Full name:

peroxiredoxin 1

Synonyms:

MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, peroxiredoxin-1, natural killer cell-enhancing factor A, natural killer-enhancing factor A, proliferation-associated gene A, proliferation-associated gene protein, thioredoxin peroxidase 2, thioredoxin-dependent peroxide reductase 2

Genomic Location:

Chr 1: 45749294-45760196

Description:

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer developme...

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This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGNNNNNNKCCAR_UNKNOWN ,  CATTGTYY_SOX9_B1 ,  TMTCGCGANR_UNKNOWN ,  TATAAA_TATA_01 ,  NF1_Q6 ,  TGCCAAR_NF1_Q6 ,  NF1_Q6_01 ,  TGTTTGY_HNF3_Q6 ,  SOX5_01 ,  TTGTTT_FOXO4_01 ,  STAT5A_04 ,  TEF_Q6 ,  TATA_01 ,  TCF11MAFG_01

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Cytogenetic Map:

1p34.1

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