QuickView for PRSS1 (gene)

Gene Symbol:

PRSS1 Homo sapiens

Full name:

protease, serine 1

Synonyms:

TRP1, TRY1, TRY4, TRYP1, trypsin-1, TCR V beta 4.1, beta-trypsin, cationic trypsinogen, digestive zymogen, nonfunctional trypsin 1, trypsinogen 1, trypsinogen A

Genomic Location:

Chr 7: 142136904-142140495

Description:

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gen...

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This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA_C ,  GATAAGR_GATA_C ,  GATA1_04 ,  TATAAA_TATA_01 ,  CAGGTG_E12_Q6

Cytogenetic Map:

7q34

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