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QuickView for PSD;jsessionid=8CBC8745A61A292CC98F5B4D21BFEFB4 (gene)


Gene Symbol:
PSD Homo sapiens Homo sapiens
Full name:
pleckstrin and Sec7 domain containing
Synonyms:
EFA6, EFA6A, PSD1, TYL, PH and SEC7 domain-containing protein 1, exchange factor for ADP-ribosylation factor guanine nucleotide factor 6, exchange factor for ARF6, exchange factor for ARF6 A, pleckstrin homology and SEC7 domain-containing protein 1, pleckstrin-Sec7 domains-containing
Genomic Location:
Chr 10: 104152366-104168891
Description:
This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
MYOD_Q6_01 TTTGCAC_MIR19A_MIR19B MYOD_01 EFC_Q6 GCANCTGNY_MYOD_Q6 PEA3_Q6 ATF4_Q2 TTGCACT_MIR130A_MIR301_MIR130B SREBP1_Q6 E2A_Q2
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 10
10q24.32





GO Molecular Function

guanyl-nucleotide exchange factor activity | GTPase binding | enzyme binding | lipid binding | phospholipid binding | molecular function regulator | anion binding | ion binding | protein binding | ARF guanyl-nucleotide exchange factor activity

GO Biological Process

guanyl-nucleotide exchange factor activity | cell differentiation | nervous system development | neurogenesis | generation of neurons | cellular process | neuron development | regulation of cellular process | cellular component organization | response to stimulus | molecular function regulator | system development | regulation of signal transduction | multicellular organism development | regulation of small GTPase mediated signal transduction | cell communication | neuron differentiation | regulation of intracellular signal transduction | anatomical structure development | cell projection organization | neuron projection development | ARF guanyl-nucleotide exchange factor activity | regulation of cell communication | signaling | cell development | regulation of Ras protein signal transduction | regulation of ARF protein signal transduction | developmental process | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

dendritic spine | cleavage furrow | dendrite | postsynaptic endosome | synapse | extrinsic component of organelle membrane | neuron projection | extrinsic component of membrane | ruffle | somatodendritic compartment | organelle membrane | cell projection membrane | cytoplasmic vesicle | cell | ruffle membrane | extrinsic component of endosome membrane | cytoplasm | intracellular organelle | dendritic tree | leading edge membrane | endosome membrane | cell projection | endomembrane system | neuron spine | postsynapse | plasma membrane | cell leading edge | vesicle | postsynaptic density | asymmetric synapse | endosome | membrane-bounded organelle | organelle | postsynaptic specialization | extrinsic component of postsynaptic endosome membrane | cell division site | cell periphery | intracellular vesicle | intracellular | membrane