Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for PSMD2 (gene)


Gene Symbol:
PSMD2 Homo sapiens Homo sapiens
Full name:
proteasome 26S subunit, non-ATPase 2
Synonyms:
P97, RPN1, S2, TRAP2, 26S proteasome non-ATPase regulatory subunit 2, 55.11 protein, TNFR-associated protein 2, proteasome (prosome, macropain) 26S subunit, non-ATPase, 2, protein 55.11, tumor necrosis factor type 1 receptor-associated protein 2
Genomic Location:
Chr 3: 185499716-185509534
Description:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which cont...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 3
3q27.1


Transcripts Names
NM_002808
NM_001278709
NM_001278708
Protein Names
Q12932
Q96I12
Q13200
Q15321



GO Molecular Function

hydrolase activity | molecular function regulator | catalytic activity | protein binding | endopeptidase activity | enzyme regulator activity | peptidase activity

GO Biological Process

protein modification by small protein removal | exocytosis | neutrophil activation | proteolysis | establishment of localization | cellular process | secretion | organic substance catabolic process | leukocyte degranulation | localization | proteolysis involved in cellular protein catabolic process | leukocyte activation | regulation of metabolic process | catabolic process | protein deubiquitination | response to stimulus | neutrophil degranulation | leukocyte activation involved in immune response | cellular protein catabolic process | secretion by cell | proteasomal protein catabolic process | protein modification process | macromolecule modification | molecular function regulator | nitrogen compound metabolic process | leukocyte mediated immunity | regulation of catalytic activity | protein catabolic process | regulation of nitrogen compound metabolic process | vesicle-mediated transport | regulated exocytosis | cell activation involved in immune response | myeloid cell activation involved in immune response | regulation of protein metabolic process | neutrophil activation involved in immune response | proteasome-mediated ubiquitin-dependent protein catabolic process | protein metabolic process | cellular macromolecule catabolic process | metabolic process | regulation of protein catabolic process | immune response | organic substance metabolic process | protein modification by small protein conjugation or removal | cell activation | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | endopeptidase activity | cellular protein metabolic process | enzyme regulator activity | cellular protein modification process | neutrophil mediated immunity | immune system process | cellular metabolic process | peptidase activity | modification-dependent protein catabolic process | post-translational protein modification | macromolecule metabolic process

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | proteasome regulatory particle | catalytic complex | cytoplasmic vesicle | cell | nuclear lumen | cytoplasmic vesicle lumen | cytoplasm | proteasome complex | intracellular organelle | ficolin-1-rich granule lumen | protein-containing complex | proteasome storage granule | secretory vesicle | endomembrane system | nucleoplasm | vesicle | extracellular exosome | proteasome regulatory particle, base subcomplex | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | membrane-enclosed lumen | secretory granule lumen | cytosolic proteasome complex | cytosol | intracellular vesicle | intracellular | proteasome accessory complex | membrane | vesicle lumen