QuickView for PSMD8;jsessionid=704E499B4FE4E691F2F70BFE2E967E00 (gene)
- Gene Symbol:
- PSMD8
Homo sapiens - Full name:
- proteasome 26S subunit, non-ATPase 8
- Synonyms:
- HEL-S-91n, HIP6, HYPF, Nin1p, Rpn12, S14, p31, 26S proteasome non-ATPase regulatory subunit 8, 26S proteasome regulatory subunit RPN12, 26S proteasome regulatory subunit S14, 26S proteasome regulatory subunit p31, epididymis secretory sperm binding protein Li 91n, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
- Genomic Location:
- Chr 19: 43557030-43566304
- Description:
-
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which cont...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
19q13.2
GO Molecular Function
GO Biological Process
protein modification by small protein removal | proteolysis | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | catabolic process | protein deubiquitination | cellular protein catabolic process | proteasomal protein catabolic process | protein modification process | macromolecule modification | nitrogen compound metabolic process | protein catabolic process | proteasome-mediated ubiquitin-dependent protein catabolic process | protein metabolic process | cellular macromolecule catabolic process | metabolic process | organic substance metabolic process | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | cellular protein metabolic process | cellular protein modification process | cellular metabolic process | modification-dependent protein catabolic process | post-translational protein modification | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | proteasome regulatory particle | catalytic complex | cell | nuclear lumen | cytoplasm | proteasome complex | intracellular organelle | protein-containing complex | nucleoplasm | proteasome regulatory particle, lid subcomplex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular | proteasome accessory complex
