QuickView for PSSA (gene)

Gene Symbol:

PTDSS1 Homo sapiens

Full name:

phosphatidylserine synthase 1

Synonyms:

LMHD, PSS1, PSSA, phosphatidylserine synthase 1, PSS-1, ptdSer synthase 1, serine-exchange enzyme I

Genomic Location:

Chr 8: 97343343-97415950

Description:

The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewsk...

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The protein encoded by this gene catalyzes the formation of phosphatidylserine from either phosphatidylcholine or phosphatidylethanolamine. Phosphatidylserine localizes to the mitochondria-associated membrane of the endoplasmic reticulum, where it serves a structural role as well as a signaling role. Defects in this gene are a cause of Lenz-Majewski hyperostotic dwarfism. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GTGCCAT_MIR183

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-183 ,  Predicted Gene Targets for miR-214

Cytogenetic Map:

8q22.1

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