Name: | PTEN Phosphohydrolase |
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Description: | A lipid phosphatase that acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION. |
Synonyms: |
PTEN Phosphatase; PTEN Protein; Phosphohydrolase, PTEN; Phosphatase and Tensin Homologue on Chromosome Ten Protein; Phosphatase, PTEN; Mutated In Multiple Advanced Cancers 1 Protein; MMAC1 Protein
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