QuickView for PTGIR (gene)

Gene Symbol:

PTGIR Homo sapiens

Full name:

prostaglandin I2 receptor

Synonyms:

IP, PRIPR, prostacyclin receptor, PGI receptor, PGI2 receptor, prostaglandin I2 (prostacyclin) receptor (IP), prostanoid IP receptor

Genomic Location:

Chr 19: 51815565-51820194

Description:

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RYTTCCTG_ETS2_B ,  GATA3_01 ,  AP2ALPHA_01 ,  CEBPDELTA_Q6 ,  CEBPB_01 ,  CAGGTG_E12_Q6 ,  ETS2_B ,  YCATTAA_UNKNOWN ,  HMGIY_Q6 ,  CCAGGGG_MIR331 ,  RGAGGAARY_PU1_Q6 ,  CCATCCA_MIR432 ,  CAGCTG_AP4_Q5 ,  NFKB_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-331 ,  Predicted Gene Targets for miR-149

Cytogenetic Map:

19q13.32

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