Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for PTPN4 (gene)


Gene Symbol:
PTPN4 Homo sapiens Homo sapiens
Full name:
protein tyrosine phosphatase, non-receptor type 4
Synonyms:
MEG, PTPMEG, PTPMEG1, tyrosine-protein phosphatase non-receptor type 4, PTPase-MEG1, megakaryocyte phosphatase, megakaryocyte protein-tyrosine phosphatase, protein tyrosine phosphatase MEG1, protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
Genomic Location:
Chr 2: 120233677-120451507
Description:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous t...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 2
2q14.2





GO Molecular Function

phosphatase activity | hydrolase activity | protein tyrosine phosphatase activity | catalytic activity | cytoskeletal protein binding | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | protein binding | phosphoric ester hydrolase activity | non-membrane spanning protein tyrosine phosphatase activity

GO Biological Process

protein dephosphorylation | response to cytokine | cellular process | phosphatase activity | response to stimulus | protein modification process | macromolecule modification | protein tyrosine phosphatase activity | nitrogen compound metabolic process | phosphorus metabolic process | phosphoprotein phosphatase activity | cellular response to cytokine stimulus | phosphate-containing compound metabolic process | protein metabolic process | response to organic substance | metabolic process | organic substance metabolic process | dephosphorylation | cellular protein metabolic process | cellular protein modification process | non-membrane spanning protein tyrosine phosphatase activity | peptidyl-tyrosine dephosphorylation | cellular metabolic process | cellular response to organic substance | macromolecule metabolic process

GO Cellular Component

cytoplasmic side of plasma membrane | intracellular membrane-bounded organelle | cell | cytoplasmic side of membrane | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | plasma membrane | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytoskeleton | intracellular | membrane