Correlation Engine 2.0
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QuickView for PTPRB (gene)

Gene Symbol:
PTPRB Homo sapiens Homo sapiens
Full name:
protein tyrosine phosphatase, receptor type B
HPTP-BETA, HPTPB, PTPB, R-PTP-BETA, VEPTP, receptor-type tyrosine-protein phosphatase beta, VE-PTP, protein tyrosine phosphatase, receptor type, beta polypeptide, vascular endothelial protein tyrosine phosphatase
Genomic Location:
Chr 12: 69196897-69317486
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one i...
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 12

GO Molecular Function

transmembrane signaling receptor activity | phosphatase activity | hydrolase activity | protein tyrosine phosphatase activity | catalytic activity | phosphoprotein phosphatase activity | signaling receptor activity | hydrolase activity, acting on ester bonds | protein binding | transmembrane receptor protein tyrosine phosphatase activity | phosphoric ester hydrolase activity

GO Biological Process

exocytosis | protein dephosphorylation | neutrophil activation | establishment of localization | blood vessel morphogenesis | cellular process | secretion | leukocyte degranulation | localization | leukocyte activation | phosphatase activity | response to stimulus | vasculature development | neutrophil degranulation | leukocyte activation involved in immune response | tube morphogenesis | secretion by cell | cardiovascular system development | protein modification process | macromolecule modification | protein tyrosine phosphatase activity | blood vessel development | system development | nitrogen compound metabolic process | multicellular organism development | phosphorus metabolic process | leukocyte mediated immunity | phosphoprotein phosphatase activity | vesicle-mediated transport | angiogenesis | regulated exocytosis | phosphate-containing compound metabolic process | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | protein metabolic process | transmembrane receptor protein tyrosine phosphatase activity | anatomical structure development | metabolic process | immune response | organic substance metabolic process | cell activation | anatomical structure formation involved in morphogenesis | dephosphorylation | cellular protein metabolic process | anatomical structure morphogenesis | developmental process | cellular protein modification process | tube development | peptidyl-tyrosine dephosphorylation | neutrophil mediated immunity | immune system process | cellular metabolic process | circulatory system development | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

secretory granule | integral component of membrane | organelle membrane | tertiary granule | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | secretory granule membrane | protein-containing complex | secretory vesicle | endomembrane system | plasma membrane | vesicle | specific granule | integral component of plasma membrane | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | tertiary granule membrane | intracellular vesicle | intracellular | specific granule membrane | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane