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QuickView for PTPRF (gene)


Gene Symbol:
PTPRF Homo sapiens Homo sapiens
Full name:
protein tyrosine phosphatase, receptor type F
Synonyms:
BNAH2, LAR, receptor-type tyrosine-protein phosphatase F, LCA-homolog, leukocyte antigen-related (LAR) PTP receptor, leukocyte antigen-related tyrosine phosphatase, leukocyte common antigen related, protein tyrosine phosphatase, receptor type, F polypeptide, receptor-linked protein-tyrosine phosphatase LAR
Genomic Location:
Chr 1: 43769134-43861930
Description:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two ...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1p34.2





GO Molecular Function

proteoglycan binding | transmembrane signaling receptor activity | protein-containing complex binding | phosphatase activity | hydrolase activity | carbohydrate derivative binding | protein tyrosine phosphatase activity | catalytic activity | anion binding | phosphoprotein phosphatase activity | signaling receptor activity | hydrolase activity, acting on ester bonds | ion binding | heparin binding | cell adhesion molecule binding | protein binding | transmembrane receptor protein tyrosine phosphatase activity | phosphoric ester hydrolase activity | glycosaminoglycan binding | chondroitin sulfate proteoglycan binding

GO Biological Process

transmembrane receptor protein tyrosine phosphatase signaling pathway | protein dephosphorylation | cell motility | regulation of neurogenesis | regulation of cell development | cell differentiation | nervous system development | neurogenesis | generation of neurons | cellular process | localization | neuron development | regulation of neuron projection development | regulation of binding | regulation of cell differentiation | regeneration | regulation of cellular process | negative regulation of receptor binding | cellular component organization | phosphatase activity | response to stimulus | response to stress | regulation of neuron projection regeneration | protein modification process | macromolecule modification | protein tyrosine phosphatase activity | regulation of cellular response to stress | locomotion | system development | nitrogen compound metabolic process | multicellular organism development | cell migration | phosphorus metabolic process | regulation of neuron differentiation | cellular response to stress | phosphoprotein phosphatase activity | enzyme linked receptor protein signaling pathway | negative regulation of binding | neuron projection regeneration | phosphate-containing compound metabolic process | cell communication | negative regulation of protein binding | neuron differentiation | protein metabolic process | transmembrane receptor protein tyrosine phosphatase activity | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | cell adhesion | neuron projection development | organic substance metabolic process | regulation of axon regeneration | regulation of response to wounding | dephosphorylation | negative regulation of molecular function | signaling | regulation of protein binding | cell development | cellular protein metabolic process | regulation of nervous system development | regulation of developmental process | developmental process | cellular protein modification process | peptidyl-tyrosine dephosphorylation | regulation of cell projection organization | cellular metabolic process | regulation of cellular component organization | signal transduction | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | intrinsic component of membrane | cell projection | plasma membrane | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cell periphery | membrane | intrinsic component of plasma membrane