QuickView for Paskin (gene)
- Gene Symbol:
- PASK
Homo sapiens - Full name:
- PAS domain containing serine/threonine kinase
- Synonyms:
- PASKIN, STK37, PAS domain-containing serine/threonine-protein kinase, per-arnt-sim (PAS) domain kinase
- Genomic Location:
- Chr 2: 241694188-241737551
- Description:
-
This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multipl...
- Orthologs:
- Mus musculus , Rattus norvegicus , Gallus gallus , Pan troglodytes , Bos taurus , Danio rerio , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
2q37.3
GO Molecular Function
ribonucleotide binding | lipid binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | phospholipid binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | phosphatidylinositol binding | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of macromolecule biosynthetic process | intracellular signal transduction | regulation of localization | regulation of carbohydrate metabolic process | negative regulation of cellular process | regulation of peptide hormone secretion | positive regulation of cellular biosynthetic process | cellular process | regulation of respiratory gaseous exchange | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of translation | positive regulation of cellular protein metabolic process | regulation of peptide secretion | response to stimulus | positive regulation of protein metabolic process | posttranscriptional regulation of gene expression | multicellular organismal homeostasis | protein serine/threonine kinase activity | negative regulation of metabolic process | protein modification process | regulation of peptide transport | macromolecule modification | nitrogen compound metabolic process | phosphorus metabolic process | regulation of hormone levels | regulation of hormone secretion | regulation of gene expression | positive regulation of cellular metabolic process | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | energy homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | homeostatic process | negative regulation of glycogen biosynthetic process | negative regulation of carbohydrate metabolic process | protein metabolic process | regulation of glucose metabolic process | metabolic process | regulation of secretion | protein kinase activity | organic substance metabolic process | negative regulation of biosynthetic process | regulation of cell communication | signaling | cellular protein metabolic process | regulation of glucagon secretion | kinase activity | cellular protein modification process | regulation of transport | regulation of glycogen biosynthetic process | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | cellular metabolic process | regulation of translation | signal transduction | regulation of signaling | positive regulation of gene expression | regulation of glycogen metabolic process | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular
