QuickView for Phosphatidylethanolamine Binding Protein (gene)

Gene Symbol:

PEBP1 Homo sapiens

Full name:

phosphatidylethanolamine binding protein 1

Synonyms:

HCNP, HCNPpp, HEL-210, HEL-S-34, HEL-S-96, PBP, PEBP, PEBP-1, RKIP, phosphatidylethanolamine-binding protein 1, Raf kinase inhibitory protein, epididymis luminal protein 210, epididymis secretory protein Li 34, epididymis secretory protein Li 96, hippocampal cholinergic neurostimulating peptide, neuropolypeptide h3, prostatic binding protein, raf kinase inhibitor protein

Genomic Location:

Chr 12: 117058253-117067773

Description:

This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal choline...

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This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Bos taurus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Cytogenetic Map:

12q24.23

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