QuickView for Pigr (gene)

Gene Symbol:

PIGR Homo sapiens

Full name:

polymeric immunoglobulin receptor

Synonyms:

polymeric immunoglobulin receptor, hepatocellular carcinoma associated protein TB6, poly-Ig receptor

Genomic Location:

Chr 1: 205168495-205186430

Description:

This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs...

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This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

IRF1_01 ,  TFIIA_Q6 ,  CAGGTG_E12_Q6 ,  CTTTAAR_UNKNOWN ,  ICSBP_Q6 ,  ISRE_01 ,  STTTCRNTTT_IRF_Q6 ,  IRF2_01 ,  CCTNTMAGA_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-542-3p

miRNA binding sites
(Source: miRecords):

hsa-miR-125b Targeted Genes

Cytogenetic Map:

1q32.1

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