QuickView for Pigs (gene)

Gene Symbol:

PIGS Homo sapiens

Full name:

phosphatidylinositol glycan anchor biosynthesis class S

Synonyms:

GPI transamidase component PIG-S, GPI transamidase subunit, phosphatidylinositol glycan, class S, phosphatidylinositol-glycan biosynthesis class S protein

Genomic Location:

Chr 17: 23904532-23922655

Description:

This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endo...

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This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  CTGAGCC_MIR24 ,  TGCACTT_MIR519C_MIR519B_MIR519A ,  GCTNWTTGK_UNKNOWN

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-24 ,  Predicted Gene Targets for miR-485-5p ,  Predicted Gene Targets for miR-93

Cytogenetic Map:

17q11.2

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