Name: | pipothiazine |
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PubChem Compound ID: | 62867 |
Molecular formula: | C24H33N3O3S2 |
Molecular weight: | 475.669 g/mol |
Synonyms: |
Pipothiazine; Pipotiazinum [INN-Latin]; Pipotiazine; 39860-99-6; EINECS 254-659-6; Pipotiazina [INN-Spanish]; 10H-Phenothiazine-2-sulfonamide,10-(3-(4-(2-hydroxyethyl)-1-piperidinyl)propyl)-N,N-dimethyl-
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Name: | pipothiazine |
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Name (isomeric): | DB01621 |
Drug Type: | small molecule |
Synonyms: |
Pipothiazine; Pipotiazina [inn-spanish]; Pipotiazinum [inn-latin]
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Brand: | Piportil Depot, Piportil L4 |
Category: | Phenothiazines, Antipsychotic Agents |
CAS number: | 39860-99-6 |
Indication: | For the maintenance treatment of chronic non-agitated schizophrenic patients. |
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Pharmacology: |
Pipotiazine has actions similar to those of other phenothiazines. Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics. However, it produces a high incidence of extra pyramidal reactions. It reduces activity ...
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Mechanism of Action: |
Pipotiazine acts as an antagonist (blocking agent) on different postsysnaptic receptors -on dopaminergic-receptors (subtypes D1, D2, D3 and D4 - different antipsychotic properties on productive and unproductive symptoms), on serotonergic-receptors (5-HT1 and 5-HT2, with anxiolytic, antidepressive and antiaggressive properties as well as an attenuat...
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Toxicity: | Symptoms of overdose include severe extrapyramidal manifestations, hypotension, lethargy and sedation. |
Affected organisms: | Humans and other mammals |
Food interaction: |
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Drug interaction: |
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