Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for Piwil1 (gene)


Gene Symbol:
PIWIL1 Homo sapiens Homo sapiens
Full name:
piwi like RNA-mediated gene silencing 1
Synonyms:
CT80.1, HIWI, MIWI, PIWI, piwi-like protein 1, piwi homolog
Genomic Location:
Chr 12: 129388567-129422826
Description:
This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacit...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 12
12q24.33





GO Molecular Function

kinase binding | nuclease activity | cation binding | protein kinase binding | enzyme binding | nucleic acid binding | mRNA binding | hydrolase activity | piRNA binding | ribonuclease activity | catalytic activity | single-stranded RNA binding | hydrolase activity, acting on ester bonds | ion binding | organic cyclic compound binding | protein binding | endoribonuclease activity | endonuclease activity | metal ion binding | heterocyclic compound binding | RNA binding

GO Biological Process

RNA metabolic process | gene silencing by RNA | nucleus organization | developmental process involved in reproduction | nuclease activity | nucleosome organization | negative regulation of cellular process | cell differentiation | male gamete generation | cellular process | chromatin organization | regulation of transposition | multicellular organismal reproductive process | gamete generation | regulation of cellular process | gene silencing | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | germ cell development | posttranscriptional regulation of gene expression | reproduction | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | negative regulation of metabolic process | spermatid differentiation | ribonuclease activity | nitrogen compound metabolic process | reproductive process | multicellular organism development | negative regulation of transposition | ATP-dependent chromatin remodeling | regulation of gene expression | cell cycle | spermatid nucleus differentiation | regulation of nitrogen compound metabolic process | piRNA metabolic process | spermatogenesis, exchange of chromosomal proteins | regulation of cellular protein metabolic process | regulation of cellular metabolic process | chromatin remodeling | regulation of protein metabolic process | endoribonuclease activity | multicellular organism reproduction | anatomical structure development | metabolic process | RNA phosphodiester bond hydrolysis, endonucleolytic | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of gene expression | RNA phosphodiester bond hydrolysis | endonuclease activity | spermatid development | DNA packaging | meiotic cell cycle | cell development | histone exchange | developmental process | organelle organization | spermatogenesis | ncRNA metabolic process | DNA conformation change | heterocycle metabolic process | chromosome organization | cellular metabolic process | regulation of translation | sperm chromatin condensation | sexual reproduction | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

pole plasm | intracellular membrane-bounded organelle | polysome | cell | ribonucleoprotein granule | cytoplasm | P granule | intracellular organelle | germ plasm | protein-containing complex | mRNA cap binding complex | ribonucleoprotein complex | membrane-bounded organelle | dense body | nucleus | organelle | cytoplasmic ribonucleoprotein granule | chromatoid body | intracellular | RNA cap binding complex