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QuickView for Plgf (gene)


Gene Symbol:
PGF Homo sapiens Homo sapiens
Full name:
placental growth factor
Synonyms:
D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760, placenta growth factor, placental growth factor, vascular endothelial growth factor-related protein
Genomic Location:
Chr 14: 74478290-74492044
Description:
This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Canis lupus familiaris Pan troglodytes Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 14
14q24.3





GO Molecular Function

signaling receptor binding | carbohydrate derivative binding | cytokine receptor binding | molecular function regulator | anion binding | vascular endothelial growth factor receptor 3 binding | identical protein binding | protein heterodimerization activity | vascular endothelial growth factor receptor binding | ion binding | heparin binding | protein binding | protein homodimerization activity | receptor regulator activity | protein dimerization activity | growth factor activity | receptor ligand activity | chemoattractant activity | glycosaminoglycan binding | growth factor receptor binding

GO Biological Process

regulation of leukocyte chemotaxis | positive regulation of locomotion | regulation of localization | morphogenesis of an epithelium | induction of positive chemotaxis | regulation of immune system process | response to hormone | positive regulation of developmental process | cell differentiation | positive regulation of epithelial cell proliferation | response to drug | positive regulation of phosphate metabolic process | positive regulation of endothelial cell proliferation | positive regulation of cellular component movement | blood vessel morphogenesis | cellular process | regulation of cell motility | epithelial tube morphogenesis | female pregnancy | renal tubule morphogenesis | regulation of chemotaxis | branching involved in ureteric bud morphogenesis | response to hypoxia | response to growth factor | positive regulation of nitrogen compound metabolic process | positive regulation of cell division | tissue development | regeneration | regulation of angiogenesis | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | epithelium development | regulation of cell division | urogenital system development | nephron tubule morphogenesis | sprouting angiogenesis | regulation of vasculature development | response to stimulus | vasculature development | cellular response to vascular endothelial growth factor stimulus | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | tube morphogenesis | reproduction | cardiovascular system development | regulation of mast cell chemotaxis | kidney development | regulation of morphogenesis of a branching structure | cell-cell signaling | molecular function regulator | positive chemotaxis | blood vessel development | locomotion | cellular response to hormone stimulus | system development | response to oxygen levels | reproductive process | regulation of signal transduction | ureteric bud development | multicellular organism development | regulation of phosphorylation | kidney morphogenesis | positive regulation of chemotaxis | kidney epithelium development | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | vascular endothelial growth factor signaling pathway | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | regulation of cellular component movement | positive regulation of mast cell chemotaxis | positive regulation of cell migration | regulation of cellular protein metabolic process | angiogenesis | mesonephric epithelium development | mesonephros development | regulation of leukocyte migration | cell communication | regulation of cellular metabolic process | renal tubule development | positive regulation of leukocyte chemotaxis | regulation of protein metabolic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | renal system development | nephron development | regulation of signaling receptor activity | receptor regulator activity | ureteric bud morphogenesis | positive regulation of protein modification process | response to organic substance | tissue morphogenesis | branching morphogenesis of an epithelial tube | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | receptor ligand activity | chemoattractant activity | nephron morphogenesis | animal organ development | regulation of endothelial cell proliferation | positive regulation of leukocyte migration | regulation of phosphate metabolic process | morphogenesis of a branching epithelium | anatomical structure formation involved in morphogenesis | regulation of cell communication | signaling | regulation of epithelial cell proliferation | positive regulation of phosphorylation | morphogenesis of a branching structure | anatomical structure morphogenesis | regulation of developmental process | developmental process | vascular endothelial growth factor receptor signaling pathway | tube development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | cellular response to organic substance | positive regulation of cell motility | circulatory system development | chemotaxis | positive regulation of angiogenesis | nephron tubule development | signal transduction | regulation of signaling | animal organ regeneration | mesonephric tubule development | cellular response to growth factor stimulus | multicellular organismal process | positive regulation of positive chemotaxis | regulation of phosphorus metabolic process

GO Cellular Component

extracellular region | extracellular space | membrane