QuickView for Plk4 (gene)

Gene Symbol:

PLK4 Homo sapiens

Full name:

polo like kinase 4

Synonyms:

MCCRP2, SAK, STK18, serine/threonine-protein kinase PLK4, Snk akin kinase, serine/threonine-protein kinase 18, serine/threonine-protein kinase Sak

Genomic Location:

Chr 4: 129021495-129039803

Description:

This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this ...

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This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_01 ,  CREB_Q4_01 ,  E2F_Q6_01 ,  CREB_Q4 ,  GTGACGY_E4F1_Q6 ,  CAGGTG_E12_Q6 ,  CCAWYNNGAAR_UNKNOWN ,  CREB_02 ,  GGGCGGR_SP1_Q6 ,  E4F1_Q6 ,  E2F1_Q3_01 ,  E47_01 ,  E2F_03 ,  E2F_Q4_01 ,  SCGGAAGY_ELK1_02 ,  CREB_Q2 ,  E2F1_Q3 ,  RCGCANGCGY_NRF1_Q6 ,  E2F_Q3 ,  CREB_Q2_01 ,  CREB_01 ,  TAXCREB_01

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Cytogenetic Map:

4q28.1

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