QuickView for Pmepa1 (gene)

Gene Symbol:

PMEPA1 Homo sapiens

Full name:

prostate transmembrane protein, androgen induced 1

Synonyms:

STAG1, TMEPAI, protein TMEPAI, solid tumor-associated 1 protein, transmembrane, prostate androgen induced RNA

Genomic Location:

Chr 20: 55656858-55719947

Description:

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this ge...

View Full Description

This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

HNF4ALPHA_Q6 ,  TTTGCAC_MIR19A_MIR19B ,  TFIIA_Q6 ,  TTTGCAG_MIR518A2 ,  RSRFC4_01 ,  TTTTGAG_MIR373 ,  E4BP4_01 ,  CTTTGCA_MIR527 ,  RSRFC4_Q2 ,  IPF1_Q4 ,  TTGCACT_MIR130A_MIR301_MIR130B ,  CTTTGA_LEF1_Q2 ,  CTAWWWATA_RSRFC4_Q2 ,  TGACCTY_ERR1_Q2 ,  MEF2_02 ,  TATAAA_TATA_01 ,  CAGGTG_E12_Q6 ,  TGCCTTA_MIR124A ,  GCAAAAA_MIR129 ,  GGGCGGR_SP1_Q6 ,  CREBP1_01 ,  GTGCCAA_MIR96 ,  CTTTAAR_UNKNOWN ,  AAAGACA_MIR511 ,  YCATTAA_UNKNOWN ,  TAATTA_CHX10_01 ,  MEF2_03 ,  TATA_01 ,  TBP_01 ,  SMAD_Q6 ,  AACTTT_UNKNOWN ,  TATTATA_MIR374 ,  CCTNTMAGA_UNKNOWN ,  MEF2_Q6_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-129 ,  Predicted Gene Targets for miR-130 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-25 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-369-3p ,  Predicted Gene Targets for miR-450 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-374 ,  Predicted Gene Targets for miR-410

View More

View Less

Cytogenetic Map:

20q13.31

search → result