Correlation Engine 2.0
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QuickView for Poli (gene)

Gene Symbol:
POLI Homo sapiens Homo sapiens
Full name:
DNA polymerase iota
RAD30B, RAD3OB, eta2, DNA polymerase iota, RAD30 homolog B, polymerase (DNA directed) iota, polymerase (DNA) iota, polymerase (DNA-directed), iota
Genomic Location:
Chr 18: 50049847-50078602
The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass t...
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Pan troglodytes Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 18

GO Molecular Function

cation binding | DNA-directed DNA polymerase activity | nucleic acid binding | DNA polymerase activity | nucleotidyltransferase activity | catalytic activity | DNA binding | damaged DNA binding | ion binding | organic cyclic compound binding | protein binding | transferase activity, transferring phosphorus-containing groups | transferase activity | metal ion binding | heterocyclic compound binding

GO Biological Process

translesion synthesis | cellular process | DNA-directed DNA polymerase activity | postreplication repair | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | response to stress | cellular nitrogen compound biosynthetic process | DNA polymerase activity | cellular nitrogen compound metabolic process | cellular biosynthetic process | DNA repair | nitrogen compound metabolic process | cellular response to DNA damage stimulus | DNA biosynthetic process | cellular response to stress | error-prone translesion synthesis | biosynthetic process | aromatic compound biosynthetic process | DNA metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | cellular macromolecule biosynthetic process | DNA synthesis involved in DNA repair | heterocycle metabolic process | cellular metabolic process | DNA replication | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | ribonucleoprotein granule | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | nuclear speck | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | cytoplasmic ribonucleoprotein granule | membrane-enclosed lumen | intracellular