QuickView for Pph22 (gene)
- Gene Symbol:
- PPH22
Saccharomyces cerevisiae - Full name:
- Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis
- Synonyms:
- PPH2, PPH22, YDL188C
- Genomic Location:
- Chr IV: 123866-124999
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Danio rerio , Canis lupus familiaris , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
protein serine/threonine phosphatase activity | cation binding | phosphatase activity | hydrolase activity | catalytic activity | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | ion binding | phosphoric ester hydrolase activity | metal ion binding
GO Biological Process
protein serine/threonine phosphatase activity | regulation of cell cycle process | actin filament-based process | protein dephosphorylation | positive regulation of cellular component organization | regulation of cellular localization | regulation of vacuole organization | regulation of localization | actin cytoskeleton organization | regulation of autophagy | negative regulation of cellular process | negative regulation of ribonucleoprotein complex localization | regulation of organelle organization | regulation of chromosome segregation | cellular process | regulation of mitotic nuclear division | regulation of chromosome separation | negative regulation of chromosome segregation | regulation of cell cycle | positive regulation of autophagosome assembly | regulation of autophagosome assembly | negative regulation of mitotic metaphase/anaphase transition | spindle checkpoint | regulation of cellular process | regulation of metabolic process | cellular component organization | phosphatase activity | regulation of mitotic cell cycle phase transition | posttranscriptional regulation of gene expression | regulation of cell cycle phase transition | supramolecular fiber organization | reproduction | cell cycle G1/S phase transition | regulation of macroautophagy | protein modification process | macromolecule modification | nitrogen compound metabolic process | reproductive process | negative regulation of mitotic cell cycle phase transition | positive regulation of organelle organization | phosphorus metabolic process | positive regulation of organelle assembly | actin filament organization | regulation of gene expression | cell cycle | positive regulation of cellular metabolic process | phosphoprotein phosphatase activity | regulation of mitotic sister chromatid separation | regulation of nitrogen compound metabolic process | positive regulation of vacuole organization | negative regulation of mitotic nuclear division | cell division | regulation of cellular protein metabolic process | mitotic spindle assembly checkpoint | mitotic cell cycle phase transition | phosphate-containing compound metabolic process | regulation of cellular metabolic process | negative regulation of mitotic sister chromatid segregation | regulation of protein metabolic process | negative regulation of mitotic sister chromatid separation | G1/S transition of mitotic cell cycle | regulation of mitotic cell cycle | protein metabolic process | regulation of sister chromatid segregation | mitotic cell cycle | metabolic process | negative regulation of mitotic cell cycle | positive regulation of cellular component biogenesis | organic substance metabolic process | cytoskeleton organization | cell budding | regulation of chromosome organization | positive regulation of autophagy | positive regulation of macroautophagy | peptidyl-serine dephosphorylation | negative regulation of cell cycle | regulation of mitotic sister chromatid segregation | dephosphorylation | negative regulation of chromosome organization | cellular protein metabolic process | organelle organization | cellular protein modification process | regulation of mitotic metaphase/anaphase transition | cell cycle phase transition | positive regulation of metabolic process | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | regulation of organelle assembly | regulation of translation | cell cycle checkpoint | regulation of cellular component organization | budding cell bud growth | macromolecule metabolic process
GO Cellular Component
condensed nuclear chromosome | chromosome | intracellular membrane-bounded organelle | chromosome, centromeric region | condensed chromosome, centromeric region | cell | nuclear lumen | intracellular organelle | condensed nuclear chromosome, centromeric region | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | nuclear periphery | condensed chromosome
