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QuickView for Prdm12 (gene)


Gene Symbol:
PRDM12 Homo sapiens Homo sapiens
Full name:
PR/SET domain 12
Synonyms:
HSAN8, PFM9, PR domain zinc finger protein 12, PR domain containing 12
Genomic Location:
Chr 9: 132529802-132548205
Description:
This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with conge...
Orthologs:
Mus musculus Rattus norvegicus Gallus gallus Pan troglodytes Danio rerio Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 9
9q34.12


Transcripts Names
NM_021619
Protein Names
A3KFK9
Q9H4Q4



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | enzyme binding | nucleic acid binding | histone methyltransferase binding | catalytic activity | chromatin binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | ion binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | double-stranded DNA binding | DNA-binding transcription factor activity | chromatin DNA binding | RNA polymerase II regulatory region sequence-specific DNA binding | transferase activity | methyltransferase activity | metal ion binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | detection of stimulus | positive regulation of cellular component organization | positive regulation of histone H3-K9 methylation | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cell differentiation | nervous system development | neurogenesis | regulation of organelle organization | generation of neurons | cellular process | positive regulation of histone H3-K9 dimethylation | neuron development | regulation of histone H3-K9 methylation | regulation of histone modification | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | regulation of histone methylation | response to stimulus | positive regulation of protein metabolic process | cellular nitrogen compound biosynthetic process | sensory perception of temperature stimulus | response to temperature stimulus | cellular nitrogen compound metabolic process | cellular biosynthetic process | detection of temperature stimulus involved in sensory perception | regulation of nucleic acid-templated transcription | detection of abiotic stimulus | system development | nitrogen compound metabolic process | positive regulation of organelle organization | multicellular organism development | positive regulation of chromosome organization | regulation of gene expression | methylation | nervous system process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | sensory perception of pain | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | detection of temperature stimulus involved in sensory perception of pain | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of RNA metabolic process | neuron differentiation | DNA-binding transcription factor activity | positive regulation of protein modification process | detection of stimulus involved in sensory perception | anatomical structure development | cell projection organization | metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | neuron projection development | organic substance metabolic process | positive regulation of histone modification | gene expression | regulation of chromosome organization | transcription, DNA-templated | sensory perception | regulation of transcription, DNA-templated | cell development | cellular macromolecule biosynthetic process | methyltransferase activity | developmental process | detection of temperature stimulus | heterocycle metabolic process | positive regulation of metabolic process | positive regulation of histone methylation | cellular metabolic process | regulation of cellular component organization | macromolecule metabolic process | multicellular organismal process | regulation of chromatin organization

GO Cellular Component

intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular