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QuickView for Protectin (gene)


Gene Symbol:
Cd59 Rattus norvegicus Rattus norvegicus
Full name:
CD59 molecule
Synonyms:
Cd59a, Cd59b, MAC-IP, MACIF, MACIP, CD59 glycoprotein, CD59 antigen, CD59 molecule, complement regulatory protein, CD59b moleucle, complement regulatory protein, Cb59b molecule, MAC-inhibitory protein, membrane attack complex inhibition factor, protectin
Genomic Location:
Chr 3: 89243599-89245129
Description:
may play a role in regulation of complement; may bind complement proteins C8 and C9
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_012925
Protein Names
P27274



GO Molecular Function

complement binding | protein binding

GO Biological Process

negative regulation of immune system process | negative regulation of complement activation | regulation of programmed cell death | regulation of immune system process | negative regulation of cellular process | positive regulation of lymphocyte activation | positive regulation of cell adhesion | negative regulation of proteolysis | negative regulation of apoptotic process | regulation of proteolysis | negative regulation of cellular metabolic process | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of immune system process | positive regulation of lymphocyte proliferation | regulation of cell proliferation | positive regulation of cell-cell adhesion | regulation of humoral immune response | positive regulation of cell activation | positive regulation of T cell activation | negative regulation of metabolic process | regulation of protein processing | regulation of cell adhesion | positive regulation of mononuclear cell proliferation | regulation of acute inflammatory response | regulation of T cell activation | regulation of gene expression | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | negative regulation of activation of membrane attack complex | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | negative regulation of immune response | regulation of complement activation | regulation of cellular metabolic process | negative regulation of protein processing | regulation of protein metabolic process | positive regulation of cell proliferation | positive regulation of leukocyte activation | negative regulation of programmed cell death | negative regulation of gene expression | negative regulation of cellular protein metabolic process | regulation of cell activation | negative regulation of protein metabolic process | regulation of T cell proliferation | regulation of cell-cell adhesion | regulation of cell death | negative regulation of cell death | regulation of inflammatory response | positive regulation of leukocyte cell-cell adhesion

GO Cellular Component

sarcolemma | intrinsic component of external side of plasma membrane | cell | intrinsic component of membrane | compact myelin | external side of plasma membrane | anchored component of plasma membrane | plasma membrane | anchored component of membrane | extracellular region | anchored component of external side of plasma membrane | extracellular space | cell periphery | cell surface | myelin sheath | membrane | intrinsic component of plasma membrane