QuickView for RACK1 (gene)
- Gene Symbol:
- RACK1
Homo sapiens - Full name:
- receptor for activated C kinase 1
- Synonyms:
- GNB2L1, Gnb2-rs1, H12.3, HLC-7, PIG21, receptor of activated protein C kinase 1, cell proliferation-inducing gene 21 protein, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, guanine nucleotide binding protein beta polypeptide 2-like 1, guanine nucleotide-binding protein subunit beta-2-like 1, guanine nucleotide-binding protein subunit beta-like protein 12.3, human lung cancer oncogene 7 protein, lung cancer oncogene 7, proliferation-inducing gene 21, protein homologous to chicken B complex protein, guanine nucleotide binding, receptor of activated protein kinase C 1, small ribosomal subunit protein RACK1
- Genomic Location:
- Chr 5: 180596534-180603512
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
5q35.3
GO Molecular Function
structural molecule activity | kinase binding | enzyme activator activity | protein kinase regulator activity | cyclin binding | protein tyrosine kinase inhibitor activity | channel regulator activity | cadherin binding | kinase regulator activity | protein kinase inhibitor activity | protein kinase binding | receptor tyrosine kinase binding | enzyme binding | nucleic acid binding | protein-containing complex binding | peptidase activator activity | enzyme inhibitor activity | ion channel inhibitor activity | signaling receptor binding | molecular function regulator | signaling adaptor activity | ribonucleoprotein complex binding | protein domain specific binding | protein kinase C binding | channel inhibitor activity | identical protein binding | peptidase activator activity involved in apoptotic process | organic cyclic compound binding | protein tyrosine kinase binding | ribosome binding | molecular adaptor activity | cell adhesion molecule binding | protein binding | protein homodimerization activity | protein phosphatase binding | kinase inhibitor activity | protein dimerization activity | protein-containing complex scaffold activity | cysteine-type endopeptidase regulator activity involved in apoptotic process | enzyme regulator activity | phosphatase binding | cysteine-type endopeptidase activator activity involved in apoptotic process | heterocyclic compound binding | SH2 domain binding | RNA binding
GO Biological Process
negative regulation of phosphorylation | regulation of hydrogen peroxide-induced cell death | positive regulation of locomotion | regulation of cysteine-type endopeptidase activity | cellular response to glucose stimulus | regulation of cellular response to oxidative stress | positive regulation of cellular component organization | regulation of response to oxidative stress | regulation of endoplasmic reticulum unfolded protein response | regulation of cellular localization | enzyme activator activity | positive regulation of apoptotic process | regulation of localization | protein kinase regulator activity | positive regulation of embryonic development | rescue of stalled ribosome | regulation of programmed cell death | negative regulation of cellular response to oxidative stress | negative regulation of phagocytosis | negative regulation of neuron death | negative regulation of cellular process | negative regulation of kinase activity | positive regulation of developmental process | regulation of protein localization to membrane | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | translational elongation | positive regulation of cyclic-nucleotide phosphodiesterase activity | positive regulation of intrinsic apoptotic signaling pathway | positive regulation of protein catabolic process | negative regulation of protein phosphorylation | cellular chemical homeostasis | positive regulation of sphingolipid biosynthetic process | glucose homeostasis | positive regulation of phosphate metabolic process | regulation of protein oligomerization | positive regulation of cellular component movement | regulation of neuron death | positive regulation of GTPase activity | protein tyrosine kinase inhibitor activity | positive regulation of cellular biosynthetic process | cellular process | negative regulation of oxidative stress-induced neuron death | channel regulator activity | regulation of cell motility | cellular homeostasis | regulation of mitochondrial membrane potential | negative regulation of signaling | negative regulation of peptidyl-serine phosphorylation | kinase regulator activity | regulation of embryonic development | protein kinase inhibitor activity | negative regulation of response to endoplasmic reticulum stress | regulation of response to cytokine stimulus | regulation of proteolysis | regulation of cell cycle | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | interspecies interaction between organisms | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | peptidase activator activity | regulation of Golgi to plasma membrane protein transport | positive regulation of cellular protein metabolic process | negative regulation of oxidative stress-induced cell death | negative regulation of response to drug | regulation of mitochondrial depolarization | regulation of establishment of cell polarity | regulation of cell division | regulation of ceramide biosynthetic process | positive regulation of cellular protein catabolic process | response to stimulus | enzyme inhibitor activity | peptide biosynthetic process | regulation of cellular protein localization | ion channel inhibitor activity | regulation of peptidyl-tyrosine phosphorylation | positive regulation of mitochondrial depolarization | positive regulation of protein metabolic process | positive regulation of peptidase activity | regulation of cellular protein catabolic process | negative regulation of protein kinase activity | regulation of response to endoplasmic reticulum stress | positive regulation of cellular protein localization | cellular nitrogen compound biosynthetic process | regulation of response to drug | posttranscriptional regulation of gene expression | positive regulation of lipid biosynthetic process | positive regulation of Golgi to plasma membrane protein transport | positive regulation of cysteine-type endopeptidase activity | response to glucose | programmed cell death | positive regulation of proteolysis involved in cellular protein catabolic process | rhythmic process | positive regulation of proteolysis | cellular nitrogen compound metabolic process | negative regulation of transport | negative regulation of endoplasmic reticulum unfolded protein response | regulation of phagocytosis | regulation of protein transport | negative regulation of metabolic process | protein modification process | regulation of peptide transport | cellular biosynthetic process | embryo development | macromolecule modification | molecular function regulator | regulation of establishment or maintenance of cell polarity | regulation of membrane potential | regulation of cellular response to stress | apoptotic process | signaling adaptor activity | regulation of protein tyrosine kinase activity | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of growth | negative regulation of phosphate metabolic process | channel inhibitor activity | multicellular organism development | negative regulation of catalytic activity | cellular glucose homeostasis | regulation of peptidase activity | regulation of catalytic activity | regulation of phosphorylation | regulation of intrinsic apoptotic signaling pathway | positive regulation of protein localization to plasma membrane | regulation of gene expression | cell cycle | regulation of membrane depolarization | negative regulation of hydrogen peroxide-induced cell death | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | regulation of cell migration | regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | cellular amide metabolic process | regulation of cellular component movement | pigmentation | peptidase activator activity involved in apoptotic process | positive regulation of hydrolase activity | translation | positive regulation of cell migration | biosynthetic process | negative regulation of protein kinase B signaling | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | positive regulation of endopeptidase activity | positive regulation of gastrulation | regulation of GTPase activity | regulation of apoptotic signaling pathway | negative regulation of hydrogen peroxide-induced neuron death | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of cellular response to drug | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of protein localization to membrane | regulation of tumor necrosis factor-mediated signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | response to monosaccharide | positive regulation of establishment of protein localization | regulation of protein phosphorylation | peptide metabolic process | regulation of cytokine-mediated signaling pathway | regulation of locomotion | positive regulation of transport | viral process | regulation of lipid biosynthetic process | negative regulation of cell growth | embryonic morphogenesis | positive regulation of molecular function | regulation of proteasomal ubiquitin-dependent protein catabolic process | regulation of protein homooligomerization | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | regulation of growth | response to organic substance | protein ubiquitination | kinase inhibitor activity | regulation of kinase activity | regulation of response to reactive oxygen species | positive regulation of ceramide biosynthetic process | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | negative regulation of endocytosis | metabolic process | negative regulation of response to oxidative stress | activation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | regulation of protein localization to plasma membrane | regulation of proteasomal protein catabolic process | cellular response to carbohydrate stimulus | regulation of vesicle-mediated transport | chemical homeostasis | positive regulation of cell death | positive regulation of cellular component biogenesis | organic substance metabolic process | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | negative regulation of cellular protein metabolic process | gene expression | amide biosynthetic process | positive regulation of programmed cell death | ion homeostasis | protein modification by small protein conjugation or removal | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | negative regulation of translation | positive regulation of protein transport | regulation of peptidyl-serine phosphorylation | regulation of sphingolipid biosynthetic process | negative regulation of protein metabolic process | regulation of cell communication | cysteine-type endopeptidase regulator activity involved in apoptotic process | negative regulation of molecular function | negative regulation of signal transduction | positive regulation of protein homooligomerization | regulation of endocytosis | negative regulation of peptidyl-tyrosine phosphorylation | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | anatomical structure morphogenesis | regulation of endopeptidase activity | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | regulation of cell growth | cellular protein modification process | regulation of gastrulation | regulation of transport | positive regulation of protein oligomerization | cysteine-type endopeptidase activator activity involved in apoptotic process | regulation of lipid metabolic process | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | positive regulation of lipid metabolic process | gastrulation | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | positive regulation of cell motility | response to carbohydrate | regulation of translation | negative regulation of protein tyrosine kinase activity | negative regulation of cell death | carbohydrate homeostasis | regulation of ubiquitin-dependent protein catabolic process | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | positive regulation of signaling | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
cytosolic ribosome | dendrite | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cell body | cell | nuclear lumen | neuronal cell body | cytoplasm | intracellular organelle | ribosome | dendritic tree | IRE1-RACK1-PP2A complex | protein-containing complex | cell projection | nucleoplasm | plasma membrane | perikaryon | midbody | ribonucleoprotein complex | vesicle | perinuclear region of cytoplasm | extracellular exosome | mitochondrion | small ribosomal subunit | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | phagocytic cup | extracellular space | cell periphery | cytosolic small ribosomal subunit | membrane-enclosed lumen | cytosol | intracellular | membrane
