QuickView for RAPGEF3;jsessionid=A87C5064490A7C1F982001C17B80E9AA (gene)
- Gene Symbol:
- RAPGEF3
Homo sapiens - Full name:
- Rap guanine nucleotide exchange factor 3
- Synonyms:
- CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910, rap guanine nucleotide exchange factor 3, 9330170P05Rik, EPAC 1, Rap guanine nucleotide exchange factor (GEF) 3, Rap1 guanine-nucleotide-exchange factor directly activated by cAMP, cAMP-regulated guanine nucleotide exchange factor I, exchange factor directly activated by cAMP 1, exchange protein directly activated by cAMP 1
- Genomic Location:
- Chr 12: 46417293-46438952
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
12q13.11
GO Molecular Function
guanyl-nucleotide exchange factor activity | GTPase binding | cyclic nucleotide binding | Rap guanyl-nucleotide exchange factor activity | cAMP binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | Ras GTPase binding | molecular function regulator | protein domain specific binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | protein binding | Ras guanyl-nucleotide exchange factor activity | small GTPase binding | purine ribonucleotide binding | adenyl ribonucleotide binding | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of supramolecular fiber organization | regulation of intracellular protein transport | guanyl-nucleotide exchange factor activity | positive regulation of cellular component organization | regulation of cellular localization | intracellular signal transduction | endothelial cell development | regulation of localization | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | endothelial cell differentiation | positive regulation of phosphate metabolic process | regulation of organelle organization | regulation of peptide hormone secretion | blood vessel morphogenesis | positive regulation of GTPase activity | response to organophosphorus | cellular process | Rap guanyl-nucleotide exchange factor activity | regulation of syncytium formation by plasma membrane fusion | positive regulation of peptidyl-serine phosphorylation | positive regulation of protein export from nucleus | regulation of histone modification | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of protein export from nucleus | tissue development | regulation of histone H3-K9 acetylation | regulation of angiogenesis | regulation of cellular process | regulation of metabolic process | small GTPase mediated signal transduction | positive regulation of cellular protein metabolic process | epithelium development | cellular response to organonitrogen compound | regulation of peptide secretion | regulation of vasculature development | response to stimulus | vasculature development | regulation of cellular protein localization | regulation of insulin secretion | positive regulation of protein metabolic process | positive regulation of cellular protein localization | positive regulation of actin filament bundle assembly | tube morphogenesis | epithelial cell development | cardiovascular system development | cellular response to organic cyclic compound | regulation of protein transport | regulation of actin cytoskeleton reorganization | regulation of peptide transport | regulation of intracellular transport | molecular function regulator | blood vessel development | positive regulation of stress fiber assembly | response to nitrogen compound | system development | positive regulation of organelle organization | endothelium development | regulation of actin cytoskeleton organization | multicellular organism development | response to purine-containing compound | regulation of actin filament organization | regulation of catalytic activity | regulation of actomyosin structure organization | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | positive regulation of intracellular protein transport | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | establishment of endothelial barrier | regulation of nitrogen compound metabolic process | positive regulation of syncytium formation by plasma membrane fusion | Rap protein signal transduction | positive regulation of hydrolase activity | second-messenger-mediated signaling | cell proliferation | regulation of cellular protein metabolic process | angiogenesis | regulation of GTPase activity | cell communication | regulation of cellular metabolic process | cyclic-nucleotide-mediated signaling | positive regulation of cytoskeleton organization | regulation of protein metabolic process | positive regulation of establishment of protein localization | regulation of protein phosphorylation | positive regulation of protein acetylation | positive regulation of transport | positive regulation of molecular function | regulation of nucleocytoplasmic transport | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | cAMP-mediated signaling | anatomical structure development | positive regulation of supramolecular fiber organization | Ras guanyl-nucleotide exchange factor activity | regulation of secretion | positive regulation of cellular component biogenesis | negative regulation of syncytium formation by plasma membrane fusion | regulation of protein secretion | cellular response to cAMP | regulation of phosphate metabolic process | regulation of chromosome organization | positive regulation of intracellular transport | response to cAMP | positive regulation of protein transport | regulation of peptidyl-serine phosphorylation | anatomical structure formation involved in morphogenesis | regulation of stress fiber assembly | regulation of cell communication | signaling | response to organic cyclic compound | cell development | positive regulation of phosphorylation | anatomical structure morphogenesis | regulation of actin filament bundle assembly | regulation of developmental process | developmental process | regulation of histone acetylation | tube development | regulation of transport | Ras protein signal transduction | response to organonitrogen compound | epithelial cell differentiation | positive regulation of metabolic process | regulation of actin filament-based process | cellular response to organic substance | regulation of protein localization | circulatory system development | positive regulation of nucleocytoplasmic transport | positive regulation of angiogenesis | regulation of cellular component organization | regulation of cytoskeleton organization | signal transduction | regulation of signaling | multicellular organismal process | regulation of chromatin organization | regulation of phosphorus metabolic process
GO Cellular Component
actin-based cell projection | cell | lamellipodium | cytoplasm | cortical cytoskeleton | intracellular organelle | actin cytoskeleton | cell projection | endomembrane system | plasma membrane | cell leading edge | vesicle | extracellular exosome | cytoplasmic region | cortical actin cytoskeleton | extracellular region | cell cortex | microvillus | membrane-bounded organelle | extracellular vesicle | filopodium | organelle | extracellular space | cell periphery | cytoskeleton | intracellular | membrane
