QuickView for RARA (gene)

Gene Symbol:

RARA Homo sapiens

Full name:

retinoic acid receptor alpha

Synonyms:

NR1B1, RAR, retinoic acid receptor alpha, RAR-alpha, nuclear receptor subfamily 1 group B member 1, nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form, retinoic acid nuclear receptor alpha variant 1, retinoic acid nuclear receptor alpha variant 2, retinoic acid receptor, alpha polypeptide

Genomic Location:

Chr 17: 35718972-35767420

Description:

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other ...

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This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  RTAAACA_FREAC2_01 ,  MYOD_01 ,  AAGCCAT_MIR135A_MIR135B ,  RYTTCCTG_ETS2_B ,  P53_DECAMER_Q2 ,  SREBP1_02 ,  FOXO4_01 ,  GCANCTGNY_MYOD_Q6 ,  LXR_DR4_Q3 ,  RNCTGNYNRNCTGNY_UNKNOWN ,  FXR_IR1_Q6 ,  AP2ALPHA_01 ,  CTAWWWATA_RSRFC4_Q2 ,  MAF_Q6 ,  TGACCTY_ERR1_Q2 ,  HEB_Q6 ,  ACTGTGA_MIR27A_MIR27B ,  GGGAGGRR_MAZ_Q6 ,  STAT_Q6 ,  TATAAA_TATA_01 ,  CAGGTA_AREB6_01 ,  STAT5B_01 ,  CACCAGC_MIR138 ,  AP4_01 ,  GR_Q6 ,  GAGCTGG_MIR337 ,  HNF4_Q6 ,  AREB6_01 ,  TGCTGAY_UNKNOWN ,  TGCCAAR_NF1_Q6 ,  RNGTGGGC_UNKNOWN ,  FREAC2_01 ,  MYOGENIN_Q6 ,  SNACANNNYSYAGA_UNKNOWN ,  CTGCAGY_UNKNOWN ,  TTCYNRGAA_STAT5B_01 ,  CTTTGT_LEF1_Q2 ,  STAT5A_01 ,  TBP_01 ,  CAGCTG_AP4_Q5 ,  LXR_Q3 ,  SMAD_Q6 ,  CDC5_01 ,  P300_01 ,  ER_Q6 ,  DR4_Q2 ,  GTTNYYNNGGTNA_UNKNOWN ,  AAGCACA_MIR218 ,  STAT5A_02 ,  TCF11_01 ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-138 ,  Predicted Gene Targets for miR-205 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-27

Cytogenetic Map:

17q21.2

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