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QuickView for RARRES2;jsessionid=7D64FD9397A0E767F3583F15DFDCE343 (gene)


Gene Symbol:
RARRES2 Homo sapiens Homo sapiens
Full name:
retinoic acid receptor responder 2
Synonyms:
HP10433, TIG2, retinoic acid receptor responder protein 2, RAR-responsive protein TIG2, chemerin, retinoic acid receptor responder (tazarotene induced) 2, tazarotene-induced gene 2 protein
Genomic Location:
Chr 7: 149666351-149669639
Description:
This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine and as an antimicrob...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 7
7q36.1


Transcripts Names
NM_002889
XM_017012491
Protein Names
Q7LE02
A0A090N7U9
Q99969



GO Molecular Function

signaling receptor binding | protein binding

GO Biological Process

regulation of leukocyte chemotaxis | positive regulation of locomotion | exocytosis | regulation of localization | defense response to other organism | establishment of localization | regulation of immune system process | platelet degranulation | positive regulation of developmental process | cell differentiation | defense response | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | defense response to Gram-negative bacterium | cellular process | secretion | positive regulation of macrophage migration | regulation of glucose import | regulation of cell motility | localization | regulation of chemotaxis | positive regulation of nitrogen compound metabolic process | regulation of fat cell differentiation | antifungal humoral response | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular lipid metabolic process | response to stimulus | defense response to fungus | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | positive regulation of glucose import | secretion by cell | embryo development | locomotion | retinoid metabolic process | response to external biotic stimulus | system development | multicellular organism development | lipid metabolic process | regulation of granulocyte chemotaxis | regulation of phosphorylation | embryonic digestive tract development | positive regulation of glucose import in response to insulin stimulus | positive regulation of chemotaxis | regulation of glucose import in response to insulin stimulus | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | vesicle-mediated transport | regulation of cellular component movement | positive regulation of cell differentiation | positive regulation of cell migration | positive regulation of glucose transmembrane transport | regulation of cellular protein metabolic process | regulated exocytosis | digestive tract development | positive regulation of macrophage chemotaxis | regulation of leukocyte migration | positive regulation of cellular response to insulin stimulus | response to bacterium | response to fungus | chordate embryonic development | regulation of cellular metabolic process | positive regulation of leukocyte chemotaxis | regulation of lipid catabolic process | humoral immune response | inflammatory response | regulation of protein metabolic process | defense response to bacterium | regulation of protein phosphorylation | regulation of locomotion | embryo development ending in birth or egg hatching | positive regulation of transport | antimicrobial humoral response | positive regulation of protein modification process | digestive system development | anatomical structure development | metabolic process | embryonic organ development | immune response | organic substance metabolic process | regulation of glucose transmembrane transport | animal organ development | positive regulation of leukocyte migration | diterpenoid metabolic process | regulation of cellular response to insulin stimulus | antifungal innate immune response | regulation of phosphate metabolic process | defense response to Gram-positive bacterium | positive regulation of phosphorylation | positive regulation of fat cell differentiation | response to biotic stimulus | isoprenoid metabolic process | regulation of developmental process | developmental process | tube development | regulation of transport | innate immune response | regulation of macrophage chemotaxis | in utero embryonic development | regulation of lipid metabolic process | positive regulation of metabolic process | immune system process | cellular metabolic process | positive regulation of cell motility | chemotaxis | response to other organism | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | extracellular matrix | cytoplasmic vesicle | cell | platelet dense granule | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | platelet dense granule lumen | secretory vesicle | endomembrane system | vesicle | extracellular region | membrane-bounded organelle | organelle | extracellular space | membrane-enclosed lumen | secretory granule lumen | intracellular vesicle | intracellular | vesicle lumen